Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR4 | P31391 | 1/20 | 0.51 |
| ▸ | TACR3 | P29371 | 1/20 | 0.48 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3560390 | 0.93 | SSTR4 (0.56) | SSTR4TACR3AKR1C1HDAC4HDAC3 | |
| SCHEMBL6620132 | 0.91 | SSTR4 (0.59) | SSTR4TACR3AKR1C1HDAC4HDAC3 | |
| SCHEMBL2712662 | 0.89 | SSTR4 (0.53) | SSTR4TACR3AKR1C1HDAC4HDAC3 | |
| SCHEMBL2363242 | 0.85 | HTT (0.48) | SSTR4TACR3AKR1C1HDAC4HDAC3 | |
| Benzoquinone SCHEMBL28168569 | 0.83 | SSTR4 (0.52) | SSTR4TACR3AKR1C1HDAC4HDAC3 | |
| SCHEMBL9640292 | 0.82 | SSTR4 (0.54) | SSTR4TACR3AKR1C1HDAC4HDAC3 | |
| Benzoquinone SCHEMBL28168470 | 0.81 | SSTR4 (0.47) | SSTR4TACR3AKR1C1HDAC4HDAC3 | |
| SCHEMBL28849376 | 0.81 | SSTR4 (0.56) | SSTR4TACR3AKR1C1HDAC4HDAC3 | |
| SCHEMBL4335228 | 0.79 | SSTR4 (0.51) | SSTR4TACR3AKR1C1HDAC4HDAC3 | |
| SCHEMBL13626300 | 0.79 | POLB (0.61) | SSTR4TACR3AKR1C1HDAC4HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009147219-A1 | NEW COMPOUNDS VII | BIOVITRUM AB (PUBL) (SE) | 2009-12-10 | — | — | WO | disclosed |