Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR4 | P31391 | 1/20 | 0.59 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.51 |
| ▸ | TACR3 | P29371 | 1/20 | 0.51 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.49 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.45 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.45 |
| ▸ | GRIA1 | P42261 | 2/20 | 0.45 |
| ▸ | GRIA2 | P42262 | 2/20 | 0.45 |
| ▸ | GRIA3 | P42263 | 2/20 | 0.45 |
| ▸ | GRIA4 | P48058 | 2/20 | 0.45 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.45 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.45 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.45 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.45 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3560390 | 0.98 | SSTR4 (0.56) | SSTR4HDAC4TACR3AKR1C1HDAC3 | |
| SCHEMBL2712662 | 0.94 | SSTR4 (0.53) | SSTR4HDAC4TACR3AKR1C1HDAC3 | |
| Benzoquinone SCHEMBL28168569 | 0.92 | SSTR4 (0.52) | SSTR4HDAC4TACR3AKR1C1HDAC3 | |
| Formic Acid SCHEMBL4335224 | 0.91 | SSTR4 (0.51) | SSTR4HDAC4TACR3AKR1C1HDAC3 | |
| SCHEMBL2363242 | 0.90 | HTT (0.48) | SSTR4HDAC4TACR3AKR1C1HDAC3 | |
| Benzoquinone SCHEMBL28168470 | 0.86 | SSTR4 (0.47) | SSTR4HDAC4TACR3AKR1C1HDAC3 | |
| SCHEMBL11692509 | 0.85 | POLB (0.60) | SSTR4HDAC4TACR3AKR1C1HDAC3 | |
| SCHEMBL28849376 | 0.85 | SSTR4 (0.56) | SSTR4HDAC4TACR3AKR1C1HDAC3 | |
| SCHEMBL7000672 | 0.84 | SSTR4 (0.46) | SSTR4HDAC4TACR3AKR1C1HDAC3 | |
| SCHEMBL9640292 | 0.83 | SSTR4 (0.54) | SSTR4HDAC4TACR3AKR1C1HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1399433-A2 | FLUOROPYRROLIDINES AS DIPEPTIDYL PEPTIDASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2004-03-24 | — | — | EP | disclosed |
| WO-2003002553-A2 | FLUOROPYRROLIDINES AS DIPEPTIDYL PEPTIDASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2003-01-09 | — | — | WO | disclosed |
| US-4319018-A | IN ACID CATALYST | MITSUI TOATSU CHEMICALS, INC. (JP) | 1982-03-09 | — | — | US | disclosed |
| EP-0031385-A1 | PROCESS FOR PREPARING POLYMETHYLENEPOLYPHENYL POLYCARBAMATE | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1981-07-08 | — | — | EP | disclosed |