SCHEMBL433525

SCHEMBL433525

CN(O)C(=O)NCC=O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5536490 0.83
SCHEMBL9287686 0.79
SCHEMBL19833264 0.76 CHRNB2 (0.33)
SCHEMBL14557534 0.72
SCHEMBL17450515 0.70 MAPT (0.36)
SCHEMBL868382 0.69
SCHEMBL14557552 0.68 KDM4E (0.50)
SCHEMBL14557533 0.68
SCHEMBL14557536 0.68
SCHEMBL18722155 0.68 EPHX1 (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 161 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220186274-A1 POLYNUCLEOTIDE MODIFICATION METHODS OXFORD NANOPORE TECHNOLOGIES PLC (GB) 2022-06-16 US claimed
US-11186857-B2 Polynucleotide modification methods OXFORD NANOPORE TECHNOLOGIES PLC (GB) 2021-11-30 US claimed
US-20200131549-A1 POLYNUCLEOTIDE MODIFICATION METHODS OXFORD NANOPORE TECHNOLOGIES LTD. (GB) 2020-04-30 US claimed
EP-3033435-B1 METHOD FOR FRAGMENTING NUCLEIC ACID BY MEANS OF TRANSPOSASE OXFORD NANOPORE TECH LTD (GB) 2019-07-24 EP claimed
EP-3033435-A1 METHOD Oxford Nanopore Technologies Limited (GB) 2016-06-22 EP claimed
WO-2015022544-A1 METHOD OXFORD NANOPORE TECHNOLOGIES LIMITED (GB) 2015-02-19 WO claimed
US-7531306-B2 Nucleic acid hybridization methods GENEOHM SCIENCES, INC. (US) 2009-05-12 US claimed
EP-1689879-A4 NUCLEIC ACID HYBRIDIZATION METHODS GENEOHM SCIENCES INC (US) 2008-08-27 EP claimed
EP-1689879-A2 NUCLEIC ACID HYBRIDIZATION METHODS Geneohm Sciences, Inc. (US) 2006-08-16 EP claimed
US-20050176035-A1 Destabilization of hybridization via DNA N-glycosylase/uridine nucleosidase, insertion of probe; kits GENEOHM SCIENCE, INC. 2005-08-11 US claimed
WO-2005049848-A2 NUCLEIC ACID HYBRIDIZATION METHODS GENEOHM SCIENCES, INC. (US) 2005-06-02 WO claimed
US-12024541-B2 Transmembrane pore consisting of two CsgG pores OXFORD NANOPORE TECHNOLOGIES PLC (GB) 2024-07-02 US disclosed
US-12018326-B2 Mutant pore OXFORD NANOPORE TECHNOLOGIES PLC (GB) 2024-06-25 US disclosed
CN-111534504-B Method of ligating one or more polynucleotide binding proteins to a target polynucleotide 牛津纳米孔科技公开有限公司 2024-06-21 CN disclosed
US-20240117421-A9 MUTANT PORES OXFORD NANOPORE TECHNOLOGIES PLC (GB) 2024-04-11 US disclosed
WO-2007095923-A1 METHOD FOR ANALYSING MULTIPLEX-MIXTURES COMPRISING NUCLEIC ACID AMPLIFICATION PRODUCTS HAVING OVERLAPPING DETECTION AREAS BIOTYPE AG (DE) 2007-08-30 WO disclosed
EP-1689879-A2 NUCLEIC ACID HYBRIDIZATION METHODS Geneohm Sciences, Inc. (US) 2006-08-16 EP disclosed
WO-2006084132-A2 REAGENTS, METHODS, AND LIBRARIES FOR BEAD-BASED SQUENCING AGENCOURT BIOSCIENCE CORP. (US) 2006-08-10 WO disclosed
US-20050176035-A1 Destabilization of hybridization via DNA N-glycosylase/uridine nucleosidase, insertion of probe; kits GENEOHM SCIENCE, INC. 2005-08-11 US disclosed
WO-2005049848-A2 NUCLEIC ACID HYBRIDIZATION METHODS GENEOHM SCIENCES, INC. (US) 2005-06-02 WO disclosed