Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 7/20 | 0.60 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | HTR2C | P28335 | 1/20 | 0.47 |
| ▸ | HTR2B | P41595 | 1/20 | 0.47 |
| ▸ | PROKR1 | Q8TCW9 | 1/20 | 0.43 |
| ▸ | PTGDR2 | Q9Y5Y4 | 6/20 | 0.43 |
| ▸ | PTGDR | Q13258 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.42 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.42 |
| ▸ | CEL | P19835 | 2/20 | 0.42 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL434242 | 0.98 | OPRL1 (0.61) | OPRL1HTR2AHTR2CHTR2BPROKR1 | |
| SCHEMBL434518 | 0.96 | OPRL1 (0.56) | OPRL1HTR2AHTR2CHTR2BPROKR1 | |
| SCHEMBL433273 | 0.92 | OPRL1 (0.59) | OPRL1HTR2AHTR2CHTR2BPROKR1 | |
| SCHEMBL23555157 | 0.86 | OPRL1 (0.49) | OPRL1HTR2AHTR2CHTR2BPROKR1 | |
| SCHEMBL28712995 | 0.85 | OPRL1 (0.54) | OPRL1HTR2AHTR2CHTR2BPROKR1 | |
| SCHEMBL23555235 | 0.83 | OPRL1 (0.50) | OPRL1PROKR1PTGDR2PTGDRPTGER2 | |
| SCHEMBL29932045 | 0.83 | SLC6A2 (0.51) | OPRL1HTR2AHTR2CHTR2B | |
| SCHEMBL3385011 | 0.83 | SLC6A2 (0.51) | OPRL1HTR2AHTR2CHTR2B | |
| SCHEMBL25706702 | 0.83 | OPRL1 (0.52) | OPRL1HTR2AHTR2CHTR2BPROKR1 | |
| SCHEMBL28867468 | 0.83 | OPRL1 (0.49) | OPRL1HTR2AHTR2CHTR2BPROKR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016026830-A1 | NOVEL FUNGICIDAL PYRAZOLE DERIVATIVES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2016-02-25 | — | — | WO | disclosed |
| EP-2595984-A1 | MICROBICIDES | Syngenta Participations AG (CH) | 2013-05-29 | — | — | EP | disclosed |
| EP-2595985-A1 | ISOXAZOLE, ISOTHIAZOLE, FURANE AND THIOPHENE COMPOUNDS AS MICROBICIDES | Syngenta Participations AG (CH) | 2013-05-29 | — | — | EP | disclosed |
| WO-2012010567-A1 | ISOXAZOLE, ISOTHIAZOLE, FURANE AND THIOPHENE COMPOUNDS AS MICROBICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2012-01-26 | — | — | WO | disclosed |
| WO-2012010568-A1 | MICROBICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2012-01-26 | — | — | WO | disclosed |