Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 7/20 | 0.56 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | HTR2C | P28335 | 1/20 | 0.47 |
| ▸ | HTR2B | P41595 | 1/20 | 0.47 |
| ▸ | PROKR1 | Q8TCW9 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | PTGDR2 | Q9Y5Y4 | 4/20 | 0.40 |
| ▸ | PTGDR | Q13258 | 3/20 | 0.40 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.39 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.39 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.39 |
| ▸ | NOS3 | P29474 | 1/20 | 0.38 |
| ▸ | NOS1 | P29475 | 1/20 | 0.38 |
| ▸ | NOS2 | P35228 | 1/20 | 0.38 |
| ▸ | CEL | P19835 | 1/20 | 0.38 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.38 |
| ▸ | FEN1 | P39748 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL433558 | 0.96 | OPRL1 (0.60) | OPRL1HTR2AHTR2CHTR2BPROKR1 | |
| SCHEMBL434242 | 0.94 | OPRL1 (0.61) | OPRL1HTR2AHTR2CHTR2BPROKR1 | |
| SCHEMBL433273 | 0.92 | OPRL1 (0.59) | OPRL1HTR2AHTR2CHTR2BPROKR1 | |
| SCHEMBL28712995 | 0.85 | OPRL1 (0.54) | OPRL1HTR2AHTR2CHTR2BPROKR1 | |
| SCHEMBL25706702 | 0.83 | OPRL1 (0.52) | OPRL1HTR2AHTR2CHTR2BPROKR1 | |
| SCHEMBL3385011 | 0.83 | SLC6A2 (0.51) | OPRL1HTR2AHTR2CHTR2BCHRNB2 | |
| SCHEMBL29932045 | 0.83 | SLC6A2 (0.51) | OPRL1HTR2AHTR2CHTR2BCHRNB2 | |
| SCHEMBL28867468 | 0.83 | OPRL1 (0.49) | OPRL1HTR2AHTR2CHTR2BPROKR1 | |
| SCHEMBL23555157 | 0.82 | OPRL1 (0.49) | OPRL1HTR2AHTR2CHTR2BPROKR1 | |
| SCHEMBL17543926 | 0.82 | OPRL1 (0.48) | OPRL1HTR2AHTR2CHTR2BPROKR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2595984-A1 | MICROBICIDES | Syngenta Participations AG (CH) | 2013-05-29 | — | — | EP | disclosed |
| EP-2595985-A1 | ISOXAZOLE, ISOTHIAZOLE, FURANE AND THIOPHENE COMPOUNDS AS MICROBICIDES | Syngenta Participations AG (CH) | 2013-05-29 | — | — | EP | disclosed |
| WO-2012010568-A1 | MICROBICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2012-01-26 | — | — | WO | disclosed |
| WO-2012010567-A1 | ISOXAZOLE, ISOTHIAZOLE, FURANE AND THIOPHENE COMPOUNDS AS MICROBICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2012-01-26 | — | — | WO | disclosed |