Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 16/20 | 0.51 |
| ▸ | SLC6A4 | P31645 | 16/20 | 0.51 |
| ▸ | SLC6A3 | Q01959 | 14/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | DRD1 | P21728 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.37 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4321716 | 0.79 | SLC6A2 (0.54) | SLC6A2SLC6A4SLC6A3CYP2D6HTR1A | |
| SCHEMBL4335624 | 0.76 | SLC6A2 (0.51) | SLC6A2SLC6A4SLC6A3CYP2D6MAPT | |
| SCHEMBL19010135 | 0.71 | SLC6A2 (0.56) | SLC6A2SLC6A4SLC6A3CYP2D6CHRM2 | |
| SCHEMBL19010138 | 0.71 | SLC6A2 (0.56) | SLC6A2SLC6A4SLC6A3CYP2D6CHRM2 | |
| SCHEMBL15131035 | 0.71 | SLC6A2 (0.56) | SLC6A2SLC6A4SLC6A3CYP2D6CHRM2 | |
| SCHEMBL4470164 | 0.71 | SLC6A2 (0.53) | SLC6A2SLC6A4SLC6A3CYP2D6CHRM2 | |
| SCHEMBL4328470 | 0.71 | SLC6A2 (0.49) | SLC6A2SLC6A4SLC6A3CYP2D6CHRM2 | |
| SCHEMBL4319928 | 0.68 | SLC6A2 (0.46) | SLC6A2SLC6A4SLC6A3CYP2D6CHRM2 | |
| SCHEMBL10957858 | 0.64 | SLC6A2 (0.59) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL4319946 | 0.64 | CHRNA7 (0.47) | SLC6A2SLC6A4SLC6A3CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009118765-A2 | NOVEL MONOAMINE RE-UPTAKE INHIBITOR | PANACEA BIOTEC LIMITED (GB) | 2009-10-01 | — | — | WO | disclosed |