Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 14/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 14/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 14/20 | 0.46 |
| ▸ | CHRM3 | P20309 | 4/20 | 0.42 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.39 |
| ▸ | DPP4 | P27487 | 1/20 | 0.39 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.39 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4326074 | 0.80 | SLC6A4 (0.50) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL4463813 | 0.78 | KDM4E (0.39) | SLC6A2SLC6A4SLC6A3CHRM3SMN1; SMN2 | |
| SCHEMBL15131035 | 0.76 | SLC6A2 (0.56) | SLC6A2SLC6A4SLC6A3CHRM3CHRM2 | |
| SCHEMBL19010138 | 0.76 | SLC6A2 (0.56) | SLC6A2SLC6A4SLC6A3CHRM3CHRM2 | |
| SCHEMBL19010135 | 0.76 | SLC6A2 (0.56) | SLC6A2SLC6A4SLC6A3CHRM3CHRM2 | |
| SCHEMBL4470164 | 0.75 | SLC6A2 (0.53) | SLC6A2SLC6A4SLC6A3CHRM3CHRM2 | |
| SCHEMBL4328470 | 0.75 | SLC6A2 (0.49) | SLC6A2SLC6A4SLC6A3CHRM3CHRM2 | |
| SCHEMBL4321716 | 0.70 | SLC6A2 (0.54) | SLC6A2SLC6A4SLC6A3CYP2D6TSHR | |
| SCHEMBL10957858 | 0.69 | SLC6A2 (0.59) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL4565016 | 0.69 | SLC6A3 (0.49) | SLC6A2SLC6A4SLC6A3OPRM1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009118765-A2 | NOVEL MONOAMINE RE-UPTAKE INHIBITOR | PANACEA BIOTEC LIMITED (GB) | 2009-10-01 | — | — | WO | claimed |
| WO-2009118765-A2 | NOVEL MONOAMINE RE-UPTAKE INHIBITOR | PANACEA BIOTEC LIMITED (GB) | 2009-10-01 | — | — | WO | disclosed |