SCHEMBL43357

SCHEMBL43357

CC(C)(C)OC(=O)N1CCC(C(=O)O)CC1

nearest known ligand 0.72

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
HPGD P15428 1/20 0.66
HSD17B10 Q99714 1/20 0.64
RECQL P46063 1/20 0.62
PTPN2 P17706 1/20 0.56
PTPN1 P18031 1/20 0.56
PTPN6 P29350 1/20 0.56
LMNA P02545 1/20 0.54
EPHX1 P07099 1/20 0.54
GPR119 Q8TDV5 1/20 0.54
USP2 O75604 1/20 0.53
SMN1; SMN2 Q16637 1/20 0.53
STS P08842 4/20 0.51
KMT2A Q03164 1/20 0.51
KDM4E B2RXH2 1/20 0.49
MAPT P10636 1/20 0.49
THRB P10828 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acetic Acid SCHEMBL7381337 0.96 HPGD (0.62) HPGDHSD17B10RECQLPTPN2PTPN1
SCHEMBL3919189 0.93 HPGD (0.77) HPGDHSD17B10RECQLPTPN2PTPN1
Methylene Chloride SCHEMBL27882742 0.93 HPGD (0.59) HPGDHSD17B10RECQLPTPN2PTPN1
SCHEMBL5425897 0.93 HPGD (0.68) HPGDHSD17B10RECQLPTPN2PTPN1
SCHEMBL8516747 0.93 HPGD (0.59) HPGDHSD17B10RECQLPTPN2PTPN1
SCHEMBL31169952 0.92 HPGD (0.70) HPGDHSD17B10RECQLPTPN2PTPN1
SCHEMBL15487760 0.91 HPGD (0.56) HPGDHSD17B10RECQLPTPN2PTPN1
SCHEMBL5169360 0.91 HPGD (0.56) HPGDHSD17B10RECQLPTPN2PTPN1
SCHEMBL42957 0.89 HPGD (0.62) HPGDHSD17B10RECQLPTPN2PTPN1
SCHEMBL42958 0.89 HPGD (0.62) HPGDHSD17B10RECQLPTPN2PTPN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 5143 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120004862-A Compound, pharmaceutical composition and application thereof 山东大学 2025-05-16 CN claimed
CN-116478143-B Donepezil derivative, preparation method and application thereof 山东第一医科大学(山东省医学科学院) 2025-05-09 CN claimed
CN-119185569-A Sustained release delivery system comprising a traceless linker 诺华股份有限公司 2024-12-27 CN claimed
CN-118930814-A Epoxy resin curing indicating compound, preparation method and composition 南方电网科学研究院有限责任公司 2024-11-12 CN claimed
CN-118164960-A Targeted p53 acetylation difunctional small molecule, preparation method and application thereof, and pharmaceutical composition 无锡市人民医院 2024-06-11 CN claimed
CN-115286583-B Diphenylamino pyrimidine-containing compound, preparation and application thereof as HDACs enzyme inhibitor 山东大学 2024-01-30 CN claimed
CN-117298108-A Androgen receptor and glucocorticoid receptor dual-target inhibitor and application thereof 浙江师范大学 2023-12-29 CN claimed
CN-116478143-A Donepezil derivative, preparation method and application thereof 山东第一医科大学(山东省医学科学院) 2023-07-25 CN claimed
CN-116178361-A Preparation of piperidine bisoxadiazole and piperidine amino thiazole substituted antitumor curcumenol derivatives and application thereof in antitumor 华东理工大学 2023-05-30 CN claimed
CN-115286583-A Diphenylaminopyrimidine-containing compound, preparation and application thereof as HDACs enzyme inhibitor 山东大学 2022-11-04 CN claimed
CN-103772477-A Glycyrrhetinic acid derivative shown in formula (I), preparation method thereof and application UNIV EAST CHINA NORMAL 2014-05-07 CN claimed
US-20130165412-A1 CANNABINOID RECEPTOR MODULATORS ARENA PHARMACEUTICALS, INC. 2013-06-27 US claimed
US-20120214766-A1 CANNABINOID RECEPTOR MODULATORS ARENA PHARMACEUTICALS, INC. 2012-08-23 US claimed
CN-102351780-A Method for synthesizing 1-tert-butoxycarbonyl-4-acetylpiperidine LANZHOU WOFENG BIOTECHNOLOGY CO LTD 2012-02-15 CN claimed
CN-101492421-A Method for preparing trifluoro acetyl substituted ring amine and its derivative SHANGHAI AQBIOPHARMA CO LTD (CN) 2009-07-29 CN claimed
EP-1507760-B1 CYANOGUANIDINE PRODRUGS LEO PHARMA AS (DK) 2007-08-01 EP claimed
US-20050215588-A1 Cyanoguanidine prodrugs LEO PHARMA A/S (DK) 2005-09-29 US claimed
EP-1507760-A1 CYANOGUANIDINE PRODRUGS Leo Pharma A/S (DK) 2005-02-23 EP claimed
WO-2003097601-A1 CYANOGUANIDINE PRODRUGS LEO PHARMA A/S (DK) 2003-11-27 WO claimed
WO-1996028445-A1 NOVEL GLUTAMATE (AMPA/KAINATE) RECEPTOR ANTAGONISTS: N-SUBSTITUTED FUSED AZACYCLOALKYLQUINOXALINEDIONES WARNER-LAMBERT COMPANY (US) 1996-09-19 WO claimed