Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.58 |
| ▸ | RECQL | P46063 | 1/20 | 0.56 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.51 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.51 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.51 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.49 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | STS | P08842 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL43357 | 0.93 | HPGD (0.66) | HPGDHSD17B10RECQLPTPN2PTPN1 | |
| Acetic Acid SCHEMBL7381337 | 0.90 | HPGD (0.62) | HPGDHSD17B10RECQLPTPN2PTPN1 | |
| SCHEMBL3919189 | 0.87 | HPGD (0.77) | HPGDHSD17B10RECQLPTPN2PTPN1 | |
| Methylene Chloride SCHEMBL27882742 | 0.87 | HPGD (0.59) | HPGDHSD17B10RECQLPTPN2PTPN1 | |
| SCHEMBL5425897 | 0.87 | HPGD (0.68) | HPGDHSD17B10RECQLPTPN2PTPN1 | |
| SCHEMBL31169952 | 0.86 | HPGD (0.70) | HPGDHSD17B10RECQLPTPN2PTPN1 | |
| SCHEMBL5169360 | 0.84 | HPGD (0.56) | HPGDHSD17B10RECQLPTPN2PTPN1 | |
| SCHEMBL15487760 | 0.84 | HPGD (0.56) | HPGDHSD17B10RECQLPTPN2PTPN1 | |
| SCHEMBL42958 | 0.83 | HPGD (0.62) | HPGDHSD17B10RECQLPTPN2PTPN1 | |
| SCHEMBL42957 | 0.83 | HPGD (0.62) | HPGDHSD17B10RECQLPTPN2PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0883405-A4 | AMIDINO PROTEASE INHIBITORS | DIMENSIONAL PHARM INC (US) | 1999-04-28 | — | — | EP | disclosed |
| EP-0883405-A1 | AMIDINO PROTEASE INHIBITORS | 3-DIMENSIONAL PHARMACEUTICALS, INC. (US) | 1998-12-16 | — | — | EP | disclosed |
| WO-1997024135-A1 | AMIDINO PROTEASE INHIBITORS | 3-DIMENSIONAL PHARMACEUTICALS, INC. (US) | 1997-07-10 | — | — | WO | disclosed |