SCHEMBL43358

SCHEMBL43358

C[N]S(C)(=O)=O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16979008 0.70
SCHEMBL862512 0.70
SCHEMBL13157640 0.70
SCHEMBL16979029 0.70 KDM4E (0.46)
SCHEMBL4657060 0.70
SCHEMBL244203 0.70
SCHEMBL8995855 0.67
SCHEMBL8543526 0.67
SCHEMBL6869439 0.67
SCHEMBL245435 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1815 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118239868-A Carbamate substituted styryl sulfone compound and preparation method and application thereof 华夏生生药业(北京)有限公司 2024-06-25 CN claimed
US-20230338389-A1 BICYCLIC HETEROCYCLES AS FGFR INHIBITORS INCYTE CORPORATION 2023-10-26 US claimed
CN-115850263-A 2, 7-disubstituted benzothiazole compound and application thereof 浙江工业大学 2023-03-28 CN claimed
US-11607416-B2 Bicyclic heterocycles as FGFR inhibitors INCYTE CORPORATION (US) 2023-03-21 US claimed
CN-115835908-A Bicyclic heterocycles as FGFR inhibitors 因赛特公司 2023-03-21 CN claimed
EP-4045151-A1 BICYCLIC HETEROCYCLES AS FGFR INHIBITORS Incyte Corporation (US) 2022-08-24 EP claimed
US-20220169639-A1 N-CONTAINING CHROMEN-4-ONE DERIVATIVES FOR THE TREATMENT AND PROPHYLAXIS OF HEPATITIS B VIRUS INFECTION HOFFMANN-LA ROCHE INC. (US) 2022-06-02 US claimed
CN-110799598-B Light-colored rosin ester composition and preparation method thereof 科腾聚合物有限责任公司 2022-03-29 CN claimed
EP-3894402-A1 N-CONTAINING CHROMEN-4-ONE DERIVATIVES FOR THE TREATMENT AND PROPHYLAXIS OF HEPATITIS B VIRUS INFECTION F. Hoffmann-La Roche AG (CH) 2021-10-20 EP claimed
US-20210198203-A1 COMPOUNDS, COMPOSITIONS AND METHODS CYTOKINETICS, INCORPORATED 2021-07-01 US claimed
EP-0223937-A1 Indoles substituted with heterocycles, intermediates, process for their preparation and medicaments Roche Diagnostics GmbH (DE) 1987-06-03 EP claimed
EP-0185345-A1 Imidazo derivatives, their preparation and medicines containing them Dr. Karl Thomae GmbH (DE) 1986-06-25 EP claimed
EP-0185346-A2 Imidazo derivatives, their preparation and medicaments containing these compounds Dr. Karl Thomae GmbH (DE) 1986-06-25 EP claimed
EP-0180352-A2 Benzene-fused heterocyclic compound FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1986-05-07 EP claimed
US-4582837-A Imidazo[4,5-b] and [4,5-c]pyridine derivatives having cardiotonic activity DR. KARL THOMAE GMBH (DE) 1986-04-15 US claimed
EP-0170117-A1 Oxindole derivatives, process for their preparation, pharmaceutical compositions containing them and intermediate compounds Roche Diagnostics GmbH (DE) 1986-02-05 EP claimed
EP-0148438-A2 Imidazole derivatives, their preparation and medicaments containing them Dr. Karl Thomae GmbH (DE) 1985-07-17 EP claimed
EP-0098448-A2 Imidazole derivatives, their preparation and medicines containing these compounds Dr. Karl Thomae GmbH (DE) 1984-01-18 EP claimed
EP-0046164-B1 UTILISATION OF PERYLENE DERIVATIVES FOR PURPOSES OF FLUORESCENCE AND NOVEL PERYLENE DERIVATIVES FRAUNHOFER-GESELLSCHAFT ZUR FÖRDERUNG DER ANGEWANDTEN FORSCHUNG E.V. (DE) 1983-11-30 EP claimed
US-4120960-A DIURETICS, SALURESIS THE BOOTS COMPANY LIMITED (GB) 1978-10-17 US claimed