⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16979029 | 0.76 | KDM4E (0.46) | — | |
| SCHEMBL15457744 | 0.70 | — | — | |
| SCHEMBL14697526 | 0.67 | — | — | |
| SCHEMBL244203 | 0.67 | — | — | |
| SCHEMBL13157640 | 0.67 | — | — | |
| SCHEMBL4657060 | 0.67 | — | — | |
| SCHEMBL43358 | 0.67 | — | — | |
| SCHEMBL1461465 | 0.64 | — | — | |
| SCHEMBL2781 | 0.64 | — | — | |
| SCHEMBL15361466 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3990451-A1 | FUSED IMIDAZOLE DERIVATIVES AS IL-17 MODULATORS | UCB Biopharma SRL (BE) | 2022-05-04 | — | — | EP | disclosed |
| EP-3990459-A1 | IMIDAZOPYRIDINE DERIVATIVES AS IL-17 MODULATORS | UCB Biopharma SRL (BE) | 2022-05-04 | — | — | EP | disclosed |
| WO-2020260426-A1 | FUSED IMIDAZOLE DERIVATIVES AS IL-17 MODULATORS | UCB Biopharma SRL (BE) | 2020-12-30 | — | — | WO | disclosed |
| WO-2020261141-A1 | IMIDAZOPYRIDINE DERIVATIVES AS IL-17 MODULATORS | UCB Biopharma SRL (BE) | 2020-12-30 | — | — | WO | disclosed |
| WO-2020260425-A1 | FUSED IMIDAZOLE DERIVATIVES AS IL-17 MODULATORS | UCB Biopharma SRL (BE) | 2020-12-30 | — | — | WO | disclosed |
| EP-2311837-B1 | Azaindoles useful as inhibitors of jak and other protein kinases | VERTEX PHARMA (US) | 2014-05-21 | — | — | EP | disclosed |
| US-5518846-A | DISAZOACETYLENIC COMPOUND | FUJI PHOTO FILM CO., LTD. (JP) | 1996-05-21 | — | — | US | disclosed |
| EP-0399403-B1 | Electrophotographic photoreceptor | FUJI PHOTO FILM CO LTD (JP) | 1995-04-26 | — | — | EP | disclosed |
| US-5106712-A | Sensitivity, durability | FUJI PHOTO FILM CO., LTD. (JP) | 1992-04-21 | — | — | US | disclosed |
| US-5073465-A | High sensitivity and durability | FUJI PHOTO FILM CO., LTD. (JP) | 1991-12-17 | — | — | US | disclosed |
| EP-0399403-A1 | Electrophotographic photoreceptor | FUJI PHOTO FILM CO., LTD. (JP) | 1990-11-28 | — | — | EP | disclosed |