Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | SCN1A | P35498 | 1/20 | 0.47 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.47 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | CTSD | P07339 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | BCHE | P06276 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL3251488 | 0.87 | LMNA (0.49) | LMNASMN1; SMN2CYP1A2CYP2D6SCN1A | |
| Bicarbonate SCHEMBL3254968 | 0.85 | LMNA (0.47) | LMNASMN1; SMN2CYP1A2CYP2D6SCN1A | |
| Acetic Acid SCHEMBL4757552 | 0.84 | LMNA (0.46) | LMNASMN1; SMN2CYP1A2CYP2D6SCN1A | |
| SCHEMBL4347373 | 0.83 | LMNA (0.55) | LMNASMN1; SMN2CYP1A2CYP2D6SCN1A | |
| Bicarbonate SCHEMBL3256726 | 0.82 | LMNA (0.54) | LMNASMN1; SMN2CYP1A2CYP2D6SCN1A | |
| Acetic Acid SCHEMBL6875088 | 0.81 | PPARG (0.42) | EPHX1NPC1PPARGPPARARAB9A | |
| Acetic Acid SCHEMBL4754474 | 0.81 | LMNA (0.53) | LMNASMN1; SMN2CYP1A2CYP2D6SCN1A | |
| Bicarbonate SCHEMBL3259766 | 0.80 | LMNA (0.52) | LMNASMN1; SMN2CYP1A2CYP2D6SCN1A | |
| Acetic Acid SCHEMBL5145744 | 0.79 | LMNA (0.51) | LMNASMN1; SMN2CYP1A2CYP2D6SCN1A | |
| Acetic Acid SCHEMBL4755059 | 0.79 | LMNA (0.48) | LMNASMN1; SMN2CYP1A2CYP2D6SCN1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2085087-A1 | Prodrugs of gaba analogs, compositions and uses thereof | Xenoport, Inc. (US) | 2009-08-05 | — | — | EP | disclosed |
| EP-1485082-A1 | METHODS FOR SYNTHESIS OF PRODRUGS FROM 1-ACYL-ALKYL DERIVATIVES AND COMPOSITIONS THEREOF | Xenoport, Inc. (US) | 2004-12-15 | — | — | EP | disclosed |
| WO-2003077902-A1 | METHODS FOR SYNTHESIS OF PRODRUGS FROM 1-ACYL-ALKYL DERIVATIVES AND COMPOSITIONS THEREOF | XENOPORT, INC. (US) | 2003-09-25 | — | — | WO | disclosed |