Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.66 |
| ▸ | LMNA | P02545 | 2/20 | 0.66 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.66 |
| ▸ | GAA | P10253 | 2/20 | 0.66 |
| ▸ | MAPT | P10636 | 2/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.66 |
| ▸ | MEN1 | O00255 | 1/20 | 0.66 |
| ▸ | USP2 | O75604 | 1/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.66 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.66 |
| ▸ | HPGD | P15428 | 1/20 | 0.66 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.66 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.66 |
| ▸ | HTT | P42858 | 1/20 | 0.66 |
| ▸ | ERN1 | O75460 | 2/20 | 0.59 |
| ▸ | PPM1B | O75688 | 1/20 | 0.59 |
| ▸ | CA12 | O43570 | 3/20 | 0.52 |
| ▸ | CA1 | P00915 | 3/20 | 0.52 |
| ▸ | CA2 | P00918 | 3/20 | 0.52 |
| ▸ | CA9 | Q16790 | 3/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10774366 | 0.98 | KDM4E (0.63) | KDM4ELMNAHSD17B10GAAMAPT | |
| SCHEMBL2404415 | 0.85 | HSD17B10 (0.65) | KDM4ELMNAHSD17B10KMT2AALOX15 | |
| SCHEMBL28566580 | 0.84 | KMT2A (0.58) | KDM4ELMNAHSD17B10KMT2AMEN1 | |
| SCHEMBL29904702 | 0.84 | KMT2A (0.58) | KDM4ELMNAHSD17B10KMT2AMEN1 | |
| SCHEMBL9796871 | 0.84 | KMT2A (0.58) | KDM4ELMNAHSD17B10KMT2AMEN1 | |
| SCHEMBL4349925 | 0.84 | LMNA (0.65) | KDM4ELMNAHSD17B10GAAMAPT | |
| SCHEMBL79989 | 0.84 | KDM4E (0.64) | KDM4ELMNAHSD17B10GAAMAPT | |
| SCHEMBL29476052 | 0.84 | KDM4E (0.64) | KDM4ELMNAHSD17B10GAAMAPT | |
| Hydrochloric Acid SCHEMBL17559530 | 0.83 | HSD17B10 (0.63) | KDM4ELMNAHSD17B10KMT2AALOX15 | |
| Sulfur Dioxide SCHEMBL28576865 | 0.83 | KMT2A (0.52) | KDM4ELMNAHSD17B10GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130078213-A1 | THROMBOPOIETIN MIMETICS | GLAXOSMITHKLINE LLC | 2013-03-28 | — | — | US | disclosed |
| EP-1889838-B1 | Thrombopoietin mimetics | SMITHKLINE BEECHAM CORP (US) | 2009-10-14 | — | — | EP | disclosed |
| EP-1889838-A1 | Thrombopoietin mimetics | SmithKline Beecham Corporation (US) | 2008-02-20 | — | — | EP | disclosed |
| EP-1864981-A1 | Thrombopoietin mimetics | SmithKline Beecham Corporation (US) | 2007-12-12 | — | — | EP | disclosed |
| US-20070129338-A1 | THROMBOPOIETIN MIMETICS | SMITHKLINE BEECHAM CORPORATION | 2007-06-07 | — | — | US | disclosed |
| US-20040019190-A1 | Thrombopoietin mimetics | NOVARTIS AG (CH) | 2004-01-29 | — | — | US | disclosed |
| EP-0291778-B1 | Process for the preparation of high temperature-resistant dielectrics | SIEMENS AG (DE) | 1994-03-16 | — | — | EP | disclosed |
| EP-0231373-B1 | A PROCESS FOR THE PRODUCTION OF A LIQUID CRYSTALLINE EXTENDED CHAIN POLYMER COMPOSITION | THE DOW CHEMICAL COMPANY (US) | 1991-01-30 | — | — | EP | disclosed |
| US-4965134-A | Method for manufacturing highly heat-resistant dielectrics | SIEMENS AKTIENGESELLSCHAFT (DE) | 1990-10-23 | — | — | US | disclosed |
| US-4847350-A | Preparation of aromatic heterocyclic polymers | THE DOW CHEMICAL COMPANY (US) | 1989-07-11 | — | — | US | disclosed |
| EP-0231373-A1 | A PROCESS FOR THE PRODUCTION OF A LIQUID CRYSTALLINE EXTENDED CHAIN POLYMER COMPOSITION. | COMMTECH INT (US) | 1987-08-12 | — | — | EP | disclosed |
| WO-1987000844-A1 | A PROCESS FOR THE PRODUCTION OF A LIQUID CRYSTALLINE EXTENDED CHAIN POLYMER COMPOSITION | COMMTECH INTERNATIONAL (US) | 1987-02-12 | — | — | WO | disclosed |
| WO-1985004178-A1 | LIQUID CRYSTALLINE POLYMER COMPOSITIONS, PROCESS, AND PRODUCTS | SRI INTERNATIONAL (US) | 1985-09-26 | — | — | WO | disclosed |
| EP-0119271-A4 | LIQUID CRYSTALLINE POLYMER COMPOSITIONS, PROCESS, AND PRODUCTS. | STANFORD RES INST INT (US) | 1985-07-01 | — | — | EP | disclosed |
| EP-0119271-A1 | LIQUID CRYSTALLINE POLYMER COMPOSITIONS, PROCESS, AND PRODUCTS. | STANFORD RES INST INT (US) | 1984-09-26 | — | — | EP | disclosed |
| EP-0119192-A1 | LIQUID CRYSTALLINE POLYMER COMPOSITIONS, PROCESS, AND PRODUCTS | SRI INTERNATIONAL (US) | 1984-09-26 | — | — | EP | disclosed |
| EP-0119202-A1 | LIQUID CRYSTALLINE POLY(2,6-BENZOTHIAZOLE) COMPOSITIONS, PROCESS AND PRODUCTS | SRI INTERNATIONAL (US) | 1984-09-26 | — | — | EP | disclosed |
| WO-1984001160-A1 | LIQUID CRYSTALLINE POLYMER COMPOSITIONS, PROCESS, AND PRODUCTS | STANFORD RES INST INT (US) | 1984-03-29 | — | — | WO | disclosed |
| WO-1984001161-A1 | LIQUID CRYSTALLINE POLY(2,6-BENZOTHIAZOLE) COMPOSITIONS, PROCESS AND PRODUCTS | STANFORD RES INST INT (US) | 1984-03-29 | — | — | WO | disclosed |
| WO-1984001162-A1 | LIQUID CRYSTALLINE POLYMER COMPOSITIONS, PROCESS, AND PRODUCTS | STANFORD RES INST INT (US) | 1984-03-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070129338-A1 | THROMBOPOIETIN MIMETICS | MPL, THPO, TEK | KDM4E 3202/4885LMNA 4580/4885HSD17B10 2374/4885 |
| US-20130078213-A1 | THROMBOPOIETIN MIMETICS | MPL, THPO, TEK | KDM4E 3202/4885LMNA 4580/4885HSD17B10 2374/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.