Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.34 |
| ▸ | ITGB3 | P05106 | 3/20 | 0.33 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.33 |
| ▸ | NPY4R | P50391 | 5/20 | 0.33 |
| ▸ | NPY1R | P25929 | 4/20 | 0.33 |
| ▸ | NPY2R | P49146 | 3/20 | 0.33 |
| ▸ | NPY5R | Q15761 | 3/20 | 0.33 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.33 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.33 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.33 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.33 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.33 |
| ▸ | ALB | P02768 | 1/20 | 0.32 |
| ▸ | SPHK1 | Q9NYA1 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26218456 | 0.87 | MEN1 (0.46) | MEN1CYP1A2KMT2ASMN1; SMN2ALOX15 | |
| SCHEMBL26727470 | 0.84 | MEN1 (0.38) | MEN1CYP1A2KMT2ASMN1; SMN2ALOX15 | |
| SCHEMBL22277155 | 0.84 | MEN1 (0.50) | MEN1CYP1A2KMT2ASMN1; SMN2ALOX15 | |
| SCHEMBL5089242 | 0.84 | MEN1 (0.50) | MEN1CYP1A2KMT2ASMN1; SMN2ALOX15 | |
| SCHEMBL18601807 | 0.84 | MEN1 (0.50) | MEN1CYP1A2KMT2ASMN1; SMN2ALOX15 | |
| SCHEMBL12674196 | 0.82 | — | — | |
| Hydrochloric Acid SCHEMBL6241672 | 0.82 | MEN1 (0.48) | MEN1CYP1A2KMT2ASMN1; SMN2ALOX15 | |
| SCHEMBL434308 | 0.82 | MEN1 (0.48) | MEN1CYP1A2KMT2ASMN1; SMN2ALOX15 | |
| SCHEMBL19145361 | 0.82 | MEN1 (0.47) | MEN1CYP1A2KMT2ASMN1; SMN2ALOX15 | |
| SCHEMBL435524 | 0.80 | MEN1 (0.43) | MEN1CYP1A2KMT2ASMN1; SMN2ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012010641-A2 | PHARMACEUTICAL COMPOSITION FOR INCREASING CELLULAR HYPOXIC TOLERANCE | UNIVERSITE DE NICE SOPHIA ANTIPOLIS (FR) | 2012-01-26 | — | — | WO | disclosed |