Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | ITGB3 | P05106 | 3/20 | 0.34 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.34 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.33 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.33 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.33 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.33 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.33 |
| ▸ | SPHK1 | Q9NYA1 | 3/20 | 0.33 |
| ▸ | RRM1 | P23921 | 1/20 | 0.32 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.32 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.31 |
| ▸ | CASP2 | P42575 | 1/20 | 0.31 |
| ▸ | ALB | P02768 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28966032 | 0.84 | MEN1 (0.44) | MEN1CYP1A2KMT2ASMN1; SMN2ALOX15 | |
| SCHEMBL17046803 | 0.82 | SPHK1 (0.39) | CYP1A2SPHK1 | |
| SCHEMBL433663 | 0.80 | MEN1 (0.47) | MEN1CYP1A2KMT2ASMN1; SMN2ALOX15 | |
| SCHEMBL22132960 | 0.80 | MEN1 (0.47) | MEN1CYP1A2KMT2ASMN1; SMN2ALOX15 | |
| SCHEMBL10725785 | 0.80 | MEN1 (0.41) | MEN1CYP1A2KMT2ASMN1; SMN2ALOX15 | |
| SCHEMBL20099658 | 0.79 | MEN1 (0.38) | MEN1CYP1A2KMT2ASMN1; SMN2ALOX15 | |
| SCHEMBL19199246 | 0.78 | MEN1 (0.44) | MEN1CYP1A2KMT2ASMN1; SMN2ALOX15 | |
| SCHEMBL29057242 | 0.78 | MEN1 (0.42) | MEN1CYP1A2KMT2ASMN1; SMN2GNAI3 | |
| SCHEMBL19889392 | 0.77 | MEN1 (0.43) | MEN1CYP1A2KMT2ASMN1; SMN2ALOX15 | |
| SCHEMBL16138483 | 0.77 | MEN1 (0.43) | MEN1CYP1A2KMT2ASMN1; SMN2ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012010641-A2 | PHARMACEUTICAL COMPOSITION FOR INCREASING CELLULAR HYPOXIC TOLERANCE | UNIVERSITE DE NICE SOPHIA ANTIPOLIS (FR) | 2012-01-26 | — | — | WO | disclosed |