SCHEMBL433670

SCHEMBL433670

[CH2]C(COCC)OC

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL295012 0.78
SCHEMBL21518237 0.75 PRKD3 (0.42)
SCHEMBL5867195 0.74
SCHEMBL27797890 0.73
SCHEMBL491421 0.73
SCHEMBL27797964 0.73
SCHEMBL10438663 0.72 PRKD3 (0.51)
SCHEMBL8086425 0.72 PRKD3 (0.51)
SCHEMBL8080756 0.72 PRKD3 (0.51)
SCHEMBL5996738 0.72 PRKD3 (0.51)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20060025434-A1 Therapeutic agents for drug/substance dependence TORAY INDUSTRIES, INC. (JP) 2006-02-02 US claimed
EP-0531382-A1 N-SUBSTITUTED-1,2,4-TRIAZOLONE COMPOUNDS FOR TREATMENT OF CARDIOVASCULAR DISORDERS G.D. SEARLE & CO. (US) 1993-03-17 EP claimed
US-4855311-A DERIVATIVES OF BENZOISOTHIAZOLE OXIME AGRO-KANESHO CO., LTD. (JP) 1989-08-08 US claimed
US-9375008-B2 Pyrazole compounds for controlling invertebrate pests BASF SE (DE) 2016-06-28 US disclosed
US-9247745-B2 Substituted pyridazines for controlling invertebrate pests BASF SE (DE) 2016-02-02 US disclosed
EP-2342196-B1 PYRAZOLE COMPOUNDS FOR CONTROLLING INVERTEBRATE PESTS BASF SE (DE) 2015-07-29 EP disclosed
US-9040537-B2 Pyridazine compounds for controlling invertebrate pests BASF SE (DE) 2015-05-26 US disclosed
EP-2595981-B1 NOVEL HETARYL (THIO)CARBOXAMIDE COMPOUNDS FOR CONTROLLING INVERTEBRATE PESTS BASF SE (DE) 2014-12-10 EP disclosed
US-20140142111-A1 Pyrazole Compounds for Controlling Invertebrate Pests BASF SE (DE) 2014-05-22 US disclosed
US-8729083-B2 Pyrazole compounds for controlling invertebrate pests BASF SE (DE) 2014-05-20 US disclosed
EP-2595981-A1 NOVEL HETARYL (THIO)CARBOXAMIDE COMPOUNDS FOR CONTROLLING INVERTEBRATE PESTS BASF SE (DE) 2013-05-29 EP disclosed
EP-0913376-A1 Process for the preparation of cyclohexanones MERCK PATENT GmbH (DE) 1999-05-06 EP disclosed
US-5760197-A YELLOW PIGMENT FOR DYEING TEXTILES DYSTAR JAPAN LTD. (JP) 1998-06-02 US disclosed
US-5719155-A CARDIOVASCULAR DISORDERS JAPAN TOBACCO INC. (JP) 1998-02-17 US disclosed
EP-0752452-A1 Hydroxyquinolone-monoazo dyes, their preparation and use DyStar Japan Ltd. (JP) 1997-01-08 EP disclosed
EP-0677519-A1 CHROMAN DERIVATIVE AND MEDICINAL USE THEREOF Japan Tobacco Inc. (JP) 1995-10-18 EP disclosed
US-5116956-A POLYAZO DYE COMPOUNDS HAVING VINYLSULFONE TYPE AND PYRIDINIUM TYPE FIBER REACTIVE GROUPS SUMITOMO CHEMICAL CO., LTD. (JP) 1992-05-26 US disclosed
US-5047432-A Antidepressants THE BOOTS COMPANY PLC (GB) 1991-09-10 US disclosed
US-4925879-A ANTIDEPRESSANTS BOOTS COMPANY, PLC (GB) 1990-05-15 US disclosed
EP-0191542-A1 Arylcyclobutylalkyl amines and their use as antidepressive medicines The Boots Company PLC (GB) 1986-08-20 EP disclosed