⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11260616 | 0.82 | HSD17B10 (0.34) | — | |
| SCHEMBL2070625 | 0.79 | TSHR (0.33) | — | |
| SCHEMBL433670 | 0.78 | — | — | |
| SCHEMBL1136403 | 0.78 | — | — | |
| SCHEMBL14921241 | 0.77 | ALDH1A1 (0.35) | — | |
| SCHEMBL1019320 | 0.76 | ALDH1A1 (0.38) | — | |
| SCHEMBL8976908 | 0.75 | USP2 (0.48) | — | |
| SCHEMBL20006 | 0.73 | — | — | |
| SCHEMBL9335108 | 0.73 | — | — | |
| SCHEMBL294499 | 0.72 | LMNA (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 82 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4960873-A | 3-pyridylisothiazoleazo compounds useful as disperse dyes | BASF AKTIENGESELLSCHAFT (DE) | 1990-10-02 | — | — | US | claimed |
| US-20230348438-A1 | PYRAZOLE COMPOUND AND PHARMACEUTICAL USE THEREOF | JAPAN TOBACCO INC. (JP) | 2023-11-02 | — | — | US | disclosed |
| US-20200317644-A1 | PYRAZOLE COMPOUND AND PHARMACEUTICAL USE THEREOF | JAPAN TOBACCO INC (JP) | 2020-10-08 | — | — | US | disclosed |
| CN-111732569-A | Liquid crystalline compound having dibenzothiophene ring, liquid crystal composition, and liquid crystal display element | 捷恩智株式会社 | 2020-10-02 | — | — | CN | disclosed |
| CN-111718332-A | 2-substituted pyrazol amino-4-substituted amino-5-pyrimidine formamide compound, composition and application thereof | 北京赛特明强医药科技有限公司 | 2020-09-29 | — | — | CN | disclosed |
| EP-3524599-A1 | PYRAZOLE COMPOUND AND PHARMACEUTICAL USE THEREOF | Japan Tobacco Inc. (JP) | 2019-08-14 | — | — | EP | disclosed |
| US-20180346449-A1 | PYRAZOLE COMPOUND AND PHARMACEUTICAL USE THEREOF | JAPAN TOBACCO INC (JP) | 2018-12-06 | — | — | US | disclosed |
| EP-3199533-A1 | PYRAZOLE COMPOUND AND PHARMACEUTICAL USE THEREOF | Japan Tobacco Inc. (JP) | 2017-08-02 | — | — | EP | disclosed |
| EP-3057958-A1 | AMINOTETRALINE AND AMINOINDANE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, AND THEIR USE IN THERAPY | AbbVie Deutschland GmbH & Co. KG (DE) | 2016-08-24 | — | — | EP | disclosed |
| EP-3057960-A1 | AMINOCHROMANE, AMINOTHIOCHROMANE AND AMINO-1,2,3,4-TETRAHYDROQUINOLINE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, AND THEIR USE IN THERAPY | AbbVie Deutschland GmbH & Co. KG (DE) | 2016-08-24 | — | — | EP | disclosed |
| US-5163996-A | Herbicides | CIBA-GEIGY CORPORATION (US) | 1992-11-17 | — | — | US | disclosed |
| EP-0510719-A1 | Benzimidazole derivatives substituted with a radical group and their use for inhibiting gastric acid secretion | AKTIEBOLAGET HÄSSLE (SE) | 1992-10-28 | — | — | EP | disclosed |
| US-5051413-A | For treatment of ischemia, antispasmodic agents, anticonvulsants and anxiety or manic conditions | CIBA-GEIGY CORPORATION (US) | 1991-09-24 | — | — | US | disclosed |
| US-4960873-A | 3-pyridylisothiazoleazo compounds useful as disperse dyes | BASF AKTIENGESELLSCHAFT (DE) | 1990-10-02 | — | — | US | disclosed |
| EP-0335234-A2 | Azo isoathiazole dyes | BASF Aktiengesellschaft (DE) | 1989-10-04 | — | — | EP | disclosed |
| EP-0302826-A2 | Process for the preparation of unsaturated amino acid compounds | CIBA-GEIGY AG (CH) | 1989-02-08 | — | — | EP | disclosed |
| EP-0233154-A2 | Unsaturated amino-acids | CIBA-GEIGY AG (CH) | 1987-08-19 | — | — | EP | disclosed |
| EP-0162217-A1 | 1,2,4-Triazacycloalcadiene derivatives | CIBA-GEIGY AG (CH) | 1985-11-27 | — | — | EP | disclosed |
| EP-0157259-A1 | 3-Mercapto-1,2,4-triazacycloalcadiene derivatives | CIBA-GEIGY AG (CH) | 1985-10-09 | — | — | EP | disclosed |
| US-4451471-A | Certain 2,4,5-tri-substituted thiazoles, pharmaceutical compositions containing same and methods of using same | CIBA-GEIGY CORPORATION (US) | 1984-05-29 | — | — | US | disclosed |