SCHEMBL4336765

SCHEMBL4336765

Cc1cccc(-c2cc(CCl)ccc2CCl)c1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 6/20 0.39
TDP1 Q9NUW8 4/20 0.39
SMN1; SMN2 Q16637 3/20 0.39
MAPK1 P28482 3/20 0.39
KMT2A Q03164 2/20 0.39
NPC1 O15118 4/20 0.38
TSHR P16473 1/20 0.38
FFAR1 O14842 1/20 0.37
FFAR4 Q5NUL3 1/20 0.37
HDAC8 Q9BY41 1/20 0.36
HDAC6 Q9UBN7 1/20 0.36
ACHE P22303 1/20 0.35
L3MBTL1 Q9Y468 2/20 0.35
TP53 P04637 1/20 0.35
MEN1 O00255 1/20 0.35
CHRNB4 P30926 1/20 0.35
CHRNA3 P32297 1/20 0.35
MAOB P27338 1/20 0.35
SLC9A1 P19634 1/20 0.35
ALDH1A1 P00352 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4329358 0.81 PTGER4 (0.41) MAOB
SCHEMBL4349827 0.81 BACE1 (0.42) RAB9ASMN1; SMN2KMT2ANPC1FFAR1
SCHEMBL4345051 0.80 CSNK2A1 (0.42) TSHRFFAR1FFAR4ALDH1A1CYP11B1
SCHEMBL3772032 0.80 MAOB (0.47) TDP1MAOBALDH1A1MAPTDYRK1A
SCHEMBL29114007 0.75 PTGDR2 (0.45) RAB9ATDP1SMN1; SMN2MAPK1KMT2A
SCHEMBL4655203 0.75 NPC1 (0.33) RAB9ATDP1KMT2ANPC1L3MBTL1
SCHEMBL4339135 0.75 SLC16A3 (0.39) KMT2AFFAR1MEN1
SCHEMBL3943893 0.75 KMT2A (0.37) TDP1KMT2AFFAR1FFAR4ACHE
SCHEMBL52147 0.73
SCHEMBL30084583 0.73

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0975710-B2 POLYMER ELECTROLUMINESCENT DEVICE MERCK PATENT GMBH (DE) 2009-06-10 EP disclosed
EP-0975710-B1 POLYMER ELECTROLUMINESCENT DEVICE KONINKL PHILIPS ELECTRONICS NV (NL) 2003-09-10 EP disclosed
EP-1310540-A1 Polymer electroluminescent device Koninklijke Philips Electronics N.V. (NL) 2003-05-14 EP disclosed
US-20020001732-A1 POLYMER ELECTROLUMINESCENT DEVICE U.S. PHILIPS CORPORATION 2002-01-03 US disclosed