SCHEMBL4329358

SCHEMBL4329358

ClCc1ccc(CCl)c(-c2cccc(-c3ccccc3)c2)c1

nearest known ligand 0.41

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
PTGER4 P35408 2/20 0.41
PTGER3 P43115 2/20 0.41
PTGER1 P34995 1/20 0.41
PTGER2 P43116 1/20 0.41
TAAR1 Q96RJ0 2/20 0.38
AGXT P21549 1/20 0.36
MGLL Q99685 1/20 0.35
MAOA P21397 1/20 0.34
KMO O15229 1/20 0.34
CSNK2A1 P68400 2/20 0.34
KCNH2 Q12809 1/20 0.34
TTR P02766 1/20 0.34
MAOB P27338 2/20 0.33
GGPS1 O95749 1/20 0.33
THRA P10827 1/20 0.33
THRB P10828 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4345051 0.89 CSNK2A1 (0.42) TAAR1CSNK2A1TTR
SCHEMBL4655203 0.83 NPC1 (0.33) TAAR1CSNK2A1TTR
SCHEMBL4336765 0.81 RAB9A (0.39) MAOB
SCHEMBL3772032 0.78 MAOB (0.47) TTRMAOB
SCHEMBL16675040 0.77 AGXT (0.52) TAAR1AGXTMAOAKMOGGPS1
SCHEMBL16675053 0.77 AGXT (0.52) TAAR1AGXTMAOAKMOGGPS1
SCHEMBL1745429 0.77 AGXT (0.55) TAAR1AGXTMAOAGGPS1
SCHEMBL28868463 0.77 LMNA (0.40)
SCHEMBL1309290 0.77 HTR7 (0.41) PTGER4PTGER3PTGER1PTGER2AGXT
SCHEMBL19002950 0.76 CSNK2A2 (0.38) CSNK2A1TTR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0975710-B2 POLYMER ELECTROLUMINESCENT DEVICE MERCK PATENT GMBH (DE) 2009-06-10 EP disclosed
EP-0975710-B1 POLYMER ELECTROLUMINESCENT DEVICE KONINKL PHILIPS ELECTRONICS NV (NL) 2003-09-10 EP disclosed
EP-1310540-A1 Polymer electroluminescent device Koninklijke Philips Electronics N.V. (NL) 2003-05-14 EP disclosed
US-20020001732-A1 POLYMER ELECTROLUMINESCENT DEVICE U.S. PHILIPS CORPORATION 2002-01-03 US disclosed