SCHEMBL4336839

SCHEMBL4336839

Cc1cc(Sc2ccccc2)cc(C)c1OCC(=O)OC(C)(C)C

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 4/20 0.39
POLB P06746 3/20 0.39
MAPT P10636 2/20 0.39
LMNA P02545 2/20 0.39
NPSR1 Q6W5P4 2/20 0.39
CYP2C9 P11712 1/20 0.39
CYP2C19 P33261 1/20 0.39
ALDH1A1 P00352 4/20 0.38
PTPN1 P18031 1/20 0.38
KMT2A Q03164 4/20 0.37
MMP13 P45452 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
PSEN1 P49768 1/20 0.36
PSEN2 P49810 1/20 0.36
APH1B Q8WW43 1/20 0.36
NCSTN Q92542 1/20 0.36
APH1A Q96BI3 1/20 0.36
PSENEN Q9NZ42 1/20 0.36
MEN1 O00255 3/20 0.36
SMN1; SMN2 Q16637 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19085962 0.83 PTPN1 (0.36) HPGDPOLBMAPTLMNANPSR1
SCHEMBL25629330 0.80 KMT2A (0.41) HPGDPOLBMAPTLMNANPSR1
SCHEMBL21784183 0.79 HPGD (0.42) HPGDPOLBMAPTLMNANPSR1
SCHEMBL98618 0.79 HPGD (0.39) HPGDPOLBMAPTLMNANPSR1
SCHEMBL24908732 0.78 KDM4E (0.47) HPGDPOLBMAPTLMNANPSR1
SCHEMBL3683299 0.77 ALDH1A1 (0.41) HPGDPOLBMAPTLMNANPSR1
SCHEMBL15584036 0.75 PTPN1 (0.36) HPGDPOLBMAPTLMNANPSR1
SCHEMBL25477165 0.74 PTPN1 (0.39) HPGDPOLBMAPTLMNANPSR1
SCHEMBL21883674 0.74 PSEN1 (0.46) HPGDPOLBMAPTLMNANPSR1
SCHEMBL24305879 0.73 PTPN1 (0.38) HPGDPOLBMAPTLMNANPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8252505-B2 Compound and method of producing same, acid generator, resist composition, and method of forming resist pattern TOKYO OHKA KOGYO CO., LTD. (JP) 2012-08-28 US disclosed
US-20090208871-A1 NOVEL COMPOUND AND METHOD OF PRODUCING SAME, ACID GENERATOR, RESIST COMPOSITION, AND METHOD OF FORMING RESIST PATTERN TOKYO OHKA KOGYO CO., LTD. (JP) 2009-08-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090208871-A1 NOVEL COMPOUND AND METHOD OF PRODUCING SAME, ACID GENERATOR, RESIST COMPOSITION, AND METHOD OF FORMING RESIST PATTERN COASY, SLC11A2, AKR7A2 HPGD 1180/4885POLB 484/4885MAPT 4392/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.