Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR4 | P46093 | 9/20 | 0.62 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.62 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4370453 | 0.94 | GPR4 (0.57) | GPR4KCNH2HRH3 | |
| SCHEMBL4376987 | 0.93 | GPR4 (0.70) | GPR4KCNH2HRH3 | |
| Hydrochloric Acid SCHEMBL4325400 | 0.92 | GPR4 (0.69) | GPR4KCNH2HRH3 | |
| SCHEMBL4325421 | 0.91 | GPR4 (0.55) | GPR4KCNH2HRH3 | |
| SCHEMBL13578544 | 0.90 | GPR4 (0.69) | GPR4KCNH2HRH3 | |
| SCHEMBL13578517 | 0.90 | GPR4 (0.56) | GPR4KCNH2HRH3 | |
| Hydrochloric Acid SCHEMBL4361147 | 0.90 | GPR4 (0.68) | GPR4KCNH2HRH3 | |
| Hydrochloric Acid SCHEMBL4338601 | 0.89 | GPR4 (0.55) | GPR4KCNH2HRH3 | |
| SCHEMBL4323618 | 0.86 | GPR4 (0.60) | GPR4KCNH2HRH3 | |
| SCHEMBL4330770 | 0.85 | GPR4 (0.59) | GPR4KCNH2HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009144201-A1 | IMIDAZOPYRIDINE DERIVATIVES AS GPR4 RECEPTOR MODULATORS | NOVARTIS AG (CH) | 2009-12-03 | — | — | WO | disclosed |