Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 19/20 | 0.53 |
| ▸ | PPARA | Q07869 | 19/20 | 0.53 |
| ▸ | PPARD | Q03181 | 5/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4337052 | 1.00 | PPARG (0.53) | PPARGPPARAPPARD | |
| SCHEMBL6653425 | 1.00 | PPARG (0.53) | PPARGPPARAPPARD | |
| SCHEMBL4329888 | 0.93 | PPARG (0.54) | PPARGPPARAPPARD | |
| SCHEMBL4329885 | 0.93 | PPARG (0.54) | PPARGPPARAPPARD | |
| SCHEMBL4329881 | 0.93 | PPARG (0.54) | PPARGPPARAPPARD | |
| SCHEMBL6651371 | 0.86 | PPARA (0.53) | PPARGPPARAPPARD | |
| SCHEMBL4336480 | 0.86 | PPARA (0.53) | PPARGPPARAPPARD | |
| SCHEMBL4336482 | 0.86 | PPARA (0.53) | PPARGPPARAPPARD | |
| SCHEMBL4327605 | 0.85 | PPARG (0.55) | PPARGPPARAPPARD | |
| SCHEMBL4327608 | 0.85 | PPARG (0.55) | PPARGPPARAPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7544835-B2 | Carboxylic acid derivative and salt thereof | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2009-06-09 | — | — | US | disclosed |