SCHEMBL4337070

SCHEMBL4337070

[CH2]CCCCC1CC/C=C\CCC1

nearest known ligand 0.36

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 3/20 0.36
CYP1A2 P05177 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7980381 0.94 CYP1A2 (0.35) SIGMAR1CYP1A2
SCHEMBL7980379 0.94 CYP1A2 (0.35) SIGMAR1CYP1A2
SCHEMBL7998008 0.85
SCHEMBL7998012 0.85
SCHEMBL4325754 0.85 CYP1A2 (0.31) CYP1A2
SCHEMBL23262 0.80 SIGMAR1 (0.52) SIGMAR1CYP1A2
SCHEMBL282389 0.80
SCHEMBL7994439 0.80 CYP1A2 (0.30) CYP1A2
SCHEMBL17941536 0.78 CYP1A2 (0.52) SIGMAR1CYP1A2
SCHEMBL17941530 0.78 CYP1A2 (0.52) SIGMAR1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2009145357-A1 IN 1-POSITION DURCH EINEN RING SUBSTITUIERTE BENZO [1, 4] DIAZEPINE ZUR VERWENDUNGS ALS ANTIDEPRESSIVA OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2009-12-03 WO disclosed