Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 18/20 | 0.60 |
| ▸ | PRKCG | P05129 | 14/20 | 0.60 |
| ▸ | PRKCB | P05771 | 14/20 | 0.60 |
| ▸ | PRKCA | P17252 | 14/20 | 0.60 |
| ▸ | KCNH2 | Q12809 | 8/20 | 0.60 |
| ▸ | PRKCD | Q05655 | 6/20 | 0.60 |
| ▸ | PRKCZ | Q05513 | 3/20 | 0.60 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.38 |
| ▸ | PDE4A | P27815 | 1/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.35 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2985115 | 0.86 | GSK3B (0.82) | GSK3BPRKCGPRKCBPRKCAKCNH2 | |
| SCHEMBL13204205 | 0.84 | GSK3B (0.65) | GSK3BPRKCGPRKCBPRKCAKCNH2 | |
| SCHEMBL3774124 | 0.75 | PRKCA (1.00) | GSK3BPRKCGPRKCBPRKCAKCNH2 | |
| SCHEMBL4343044 | 0.75 | GSK3B (0.66) | GSK3BPRKCGPRKCBPRKCAKCNH2 | |
| SCHEMBL5803991 | 0.73 | GSK3B (0.83) | GSK3BPRKCGPRKCBPRKCAKCNH2 | |
| SCHEMBL5759641 | 0.73 | PRKCA (0.95) | GSK3BPRKCGPRKCBPRKCAKCNH2 | |
| SCHEMBL5758194 | 0.71 | GSK3B (0.88) | GSK3BPRKCGPRKCBPRKCAKCNH2 | |
| SCHEMBL5758391 | 0.69 | GSK3B (0.90) | GSK3BPRKCGPRKCBPRKCAKCNH2 | |
| SCHEMBL5790814 | 0.69 | PRKCA (0.86) | GSK3BPRKCGPRKCBPRKCAKCNH2 | |
| SCHEMBL5757630 | 0.67 | GSK3B (0.84) | GSK3BPRKCGPRKCBPRKCAKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9845460-B2 | Treatment of pluripotent cells | JANSSEN BIOTECH, INC. (US) | 2017-12-19 | — | — | US | disclosed |
| US-20140080210-A1 | Treatment of Pluripotent Cells | JANSSEN BIOTECH, INC. (US) | 2014-03-20 | — | — | US | disclosed |
| US-8623648-B2 | Treatment of pluripotent cells | JANSSEN BIOTECH, INC. (US) | 2014-01-07 | — | — | US | disclosed |
| US-20090325293-A1 | TREATMENT OF PLURIPOTENT CELLS | JANSSEN BIOTECH, INC. | 2009-12-31 | — | — | US | disclosed |