Ethylene

Ethylene

SCHEMBL4337285

C=C.CC(Cl)(C1C=Cc2ccccc21)C1C=Cc2ccccc21.[Hf]

nearest known ligand 0.33

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR6 P50406 1/20 0.33
HTR2A P28223 2/20 0.32
SIGMAR1 Q99720 2/20 0.31
BRD4 O60885 1/20 0.30
CCL2 P13500 1/20 0.30
KDM4E B2RXH2 1/20 0.30
LMNA P02545 1/20 0.30
TP53 P04637 1/20 0.30
CHRM2 P08172 1/20 0.30
CYP3A4 P08684 1/20 0.30
CYP2D6 P10635 1/20 0.30
CHRM1 P11229 1/20 0.30
DRD2 P14416 1/20 0.30
ADRA2B P18089 1/20 0.30
ADRA2C P18825 1/20 0.30
NFKB1 P19838 1/20 0.30
CHRM3 P20309 1/20 0.30
SLC6A2 P23975 1/20 0.30
HTR2C P28335 1/20 0.30
ADRA1A P35348 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ethylene SCHEMBL1535509 0.96 HTR6 (0.33) HTR6HTR2ASIGMAR1BRD4CCL2
SCHEMBL8971102 0.94 HTR2A (0.35) HTR6HTR2ASIGMAR1BRD4CCL2
SCHEMBL8971418 0.83 HTR2A (0.35) HTR6HTR2ASIGMAR1BRD4CCL2
SCHEMBL1452608 0.79 HTR6 (0.41) HTR6HTR2ASIGMAR1BRD4CCL2
SCHEMBL1030004 0.79 HTR2A (0.38) HTR6HTR2ASIGMAR1BRD4CCL2
SCHEMBL8853566 0.77 RET (0.33) HTR6HTR2ASIGMAR1RET
Lithium SCHEMBL5702700 0.77 HTR6 (0.40) HTR6HTR2ASIGMAR1BRD4CCL2
SCHEMBL9144761 0.77 HTR2A (0.36) HTR6HTR2ASIGMAR1BRD4CCL2
Lithium SCHEMBL9145158 0.77 HTR2A (0.36) HTR6HTR2ASIGMAR1BRD4CCL2
SCHEMBL9144758 0.77 HTR2A (0.36) HTR6HTR2ASIGMAR1BRD4CCL2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7592403-B2 Ethylene polymer, preparation process thereof and molded articles of the same MITSUI CHEMICALS, INC. (JP) 2009-09-22 US claimed
US-7592403-B2 Ethylene polymer, preparation process thereof and molded articles of the same MITSUI CHEMICALS, INC. (JP) 2009-09-22 US disclosed
US-20050267273-A1 Ethylene polymer, preparation process thereof and molded articles of the same MITSUI CHEMICALS, INC. 2005-12-01 US disclosed
EP-1231229-A2 Ethylene polymer, preparation process thereof and molded articles of the same Mitsui Chemicals, Inc. (JP) 2002-08-14 EP disclosed
US-20020107343-A1 Ethylene polymer, preparation process thereof and molded articles of the same MITSUI CHEMICALS, INC. 2002-08-08 US disclosed