Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 3/20 | 0.46 |
| ▸ | PDE3A | Q14432 | 3/20 | 0.46 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 4/20 | 0.37 |
| ▸ | MAOB | P27338 | 4/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | GSK3A | P49840 | 2/20 | 0.33 |
| ▸ | GSK3B | P49841 | 2/20 | 0.33 |
| ▸ | MGAM | O43451 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | SI | P14410 | 1/20 | 0.33 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.33 |
| ▸ | KIF11 | P52732 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4337388 | 0.81 | PDE3B (0.59) | PDE3BPDE3ACYP11B1CYP11B2MAOA | |
| SCHEMBL2798580 | 0.79 | PDE3B (0.44) | PDE3BPDE3ACYP11B1CYP11B2MAOA | |
| SCHEMBL3250152 | 0.78 | PDE3B (0.46) | PDE3BPDE3ACYP11B1CYP11B2MAOA | |
| SCHEMBL14476308 | 0.78 | PDE3B (0.43) | PDE3BPDE3ACYP11B1CYP11B2MAOA | |
| SCHEMBL620725 | 0.78 | PDE3B (0.46) | PDE3BPDE3ACYP11B1CYP11B2MAOA | |
| SCHEMBL13356482 | 0.78 | PDE3B (0.43) | PDE3BPDE3ACYP11B1CYP11B2MAOA | |
| SCHEMBL30047289 | 0.76 | PDE3B (0.46) | PDE3BPDE3ACYP11B1CYP11B2MAOA | |
| SCHEMBL2292992 | 0.76 | PDE3B (0.46) | PDE3BPDE3ACYP11B1CYP11B2MAOA | |
| SCHEMBL8340212 | 0.74 | PDE3B (0.42) | PDE3BPDE3ACYP11B1CYP11B2MAOA | |
| SCHEMBL3248415 | 0.74 | ALDH1A1 (0.48) | PDE3BPDE3AMAOAMAOBEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2022793-B1 | NOVEL HETEROCYCLIC COMPOUND OR SALT THEREOF AND INTERMEDIATE THEREOF | TOYAMA CHEMICAL CO LTD (JP) | 2014-06-04 | — | — | EP | disclosed |
| EP-2022793-A1 | NOVEL HETEROCYCLIC COMPOUND OR SALT THEREOF AND INTERMEDIATE THEREOF | TOYAMA CHEMICAL CO., LTD. (JP) | 2009-02-11 | — | — | EP | disclosed |