Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR1 | Q9Y271 | 2/20 | 0.36 |
| ▸ | PTPN2 | P17706 | 4/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 7/20 | 0.32 |
| ▸ | CA9 | Q16790 | 7/20 | 0.32 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA4 | P22748 | 1/20 | 0.32 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13785272 | 0.96 | THRB (0.34) | CYSLTR1PTPN2PTPN1MAPTALDH1A1 | |
| SCHEMBL4333267 | 0.95 | MAPT (0.38) | CYSLTR1PTPN2PTPN1MAPTALDH1A1 | |
| SCHEMBL25277712 | 0.93 | MAPT (0.40) | PTPN2PTPN1MAPTALDH1A1MEN1 | |
| SCHEMBL30457050 | 0.93 | MAPT (0.40) | PTPN2PTPN1MAPTALDH1A1MEN1 | |
| SCHEMBL30456612 | 0.93 | HDAC1 (0.40) | CYSLTR1PTPN2PTPN1MAPTALDH1A1 | |
| SCHEMBL25269639 | 0.93 | HDAC1 (0.40) | CYSLTR1PTPN2PTPN1MAPTALDH1A1 | |
| SCHEMBL25226273 | 0.93 | HDAC1 (0.40) | CYSLTR1PTPN2PTPN1MAPTALDH1A1 | |
| SCHEMBL30457662 | 0.93 | HDAC1 (0.40) | CYSLTR1PTPN2PTPN1MAPTALDH1A1 | |
| SCHEMBL25227956 | 0.93 | HDAC1 (0.40) | CYSLTR1PTPN2PTPN1MAPTALDH1A1 | |
| SCHEMBL30457539 | 0.93 | HDAC1 (0.40) | CYSLTR1PTPN2PTPN1MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1169293-B1 | LIQUID CRYSTAL COMPOUNDS | ROLIC AG (CH) | 2009-07-22 | — | — | EP | disclosed |
| US-6733690-B1 | ACRYLIC ESTER POLYMERS | ROLIC AG (CH) | 2004-05-11 | — | — | US | disclosed |