Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM2B | Q8NHM5 | 11/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | MGLL | Q99685 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4338025 | 1.00 | KDM2B (0.41) | KDM2BKMT2AHTTESR1ESR2 | |
| SCHEMBL4026114 | 1.00 | KDM2B (0.41) | KDM2BKMT2AHTTESR1ESR2 | |
| SCHEMBL4021398 | 0.95 | KDM2B (0.45) | KDM2BKMT2AHTTMEN1NPSR1 | |
| SCHEMBL4025770 | 0.93 | KDM2B (0.41) | KDM2BKMT2AHTTESR1ESR2 | |
| SCHEMBL4024540 | 0.93 | MEN1 (0.35) | KDM2BKMT2AMEN1MGLLALDH1A1 | |
| SCHEMBL4024525 | 0.93 | MEN1 (0.35) | KDM2BKMT2AMEN1MGLLALDH1A1 | |
| SCHEMBL13720775 | 0.93 | MEN1 (0.35) | KDM2BKMT2AMEN1MGLLALDH1A1 | |
| SCHEMBL4021139 | 0.92 | KDM2B (0.43) | KDM2BKMT2AHTTESR1ESR2 | |
| SCHEMBL4028033 | 0.91 | KDM2B (0.40) | KDM2BKMT2AHTTESR1ESR2 | |
| SCHEMBL4029178 | 0.90 | KDM2B (0.43) | KDM2BKMT2AHTTMEN1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7572814-B2 | 3,5-dibenzoyl-4-phenyl-piperidine anti-cancer compounds | CYTOKINETICS, INCORPORATED (US) | 2009-08-11 | — | — | US | claimed |