Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR4 | P31391 | 19/20 | 0.49 |
| ▸ | SSTR1 | P30872 | 4/20 | 0.47 |
| ▸ | SSTR2 | P30874 | 4/20 | 0.47 |
| ▸ | SSTR3 | P32745 | 4/20 | 0.47 |
| ▸ | SSTR5 | P35346 | 4/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL3276496 | 0.99 | SSTR4 (0.48) | SSTR4SSTR1SSTR2SSTR3SSTR5 | |
| Bromide SCHEMBL3275381 | 0.90 | SSTR4 (0.47) | SSTR4SSTR1SSTR2SSTR3SSTR5 | |
| SCHEMBL23734949 | 0.82 | PARP1 (0.62) | POLB | |
| Hydrochloric Acid SCHEMBL3276373 | 0.79 | SSTR4 (0.54) | SSTR4SSTR1SSTR2SSTR3SSTR5 | |
| SCHEMBL3282996 | 0.73 | ADRB1 (0.50) | SSTR4 | |
| SCHEMBL8257527 | 0.73 | HPGD (0.52) | POLB | |
| SCHEMBL25405889 | 0.73 | POLB (0.49) | POLB | |
| Hydrochloric Acid SCHEMBL3276614 | 0.72 | ADRB1 (0.49) | SSTR4 | |
| SCHEMBL11799044 | 0.72 | POLB (0.61) | POLB | |
| Hydrochloric Acid SCHEMBL3281370 | 0.71 | ADRB1 (0.48) | SSTR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2123644-A1 | BENZOXAZEPINE DERIVATIVES AND USE THEREOF | Takeda Pharmaceutical Company Limited (JP) | 2009-11-25 | — | — | EP | disclosed |