Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX3 | P56373 | 20/20 | 0.82 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1000164 | 0.90 | P2RX3 (1.00) | P2RX3 | |
| SCHEMBL1000162 | 0.90 | P2RX3 (1.00) | P2RX3 | |
| SCHEMBL997921 | 0.89 | P2RX3 (1.00) | P2RX3 | |
| SCHEMBL997262 | 0.89 | P2RX3 (1.00) | P2RX3 | |
| SCHEMBL998086 | 0.89 | P2RX3 (1.00) | P2RX3 | |
| SCHEMBL4355294 | 0.89 | P2RX3 (0.83) | P2RX3 | |
| SCHEMBL999407 | 0.81 | P2RX3 (1.00) | P2RX3 | |
| SCHEMBL999414 | 0.81 | P2RX3 (1.00) | P2RX3 | |
| SCHEMBL998519 | 0.81 | P2RX3 (1.00) | P2RX3 | |
| SCHEMBL1048702 | 0.81 | P2RX3 (1.00) | P2RX3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2136639-A1 | PYRID-2-YL FUSED HETEROCYCLIC COMPOUNDS, AND COMPOSITIONS AND USES THEREOF | Renovis, Inc. (US) | 2009-12-30 | — | — | EP | claimed |
| WO-2008123963-A1 | PYRID-2-YL FUSED HETEROCYCLIC COMPOUNDS, AND COMPOSITIONS AND USES THEREOF | RENOVIS, INC. (US) | 2008-10-16 | — | — | WO | claimed |