Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | PGR | P06401 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | PDE4A | P27815 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | HRH1 | P35367 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2018313 | 0.89 | HPGD (0.54) | HPGDALDH1A1LMNAMAPK1HTT | |
| SCHEMBL4607568 | 0.86 | HPGD (0.54) | HPGDALDH1A1LMNAMAPK1HTT | |
| SCHEMBL29384880 | 0.82 | HPGD (0.59) | HPGDALDH1A1LMNAMAPK1HTT | |
| SCHEMBL93397 | 0.82 | HPGD (0.59) | HPGDALDH1A1LMNAMAPK1HTT | |
| SCHEMBL4339862 | 0.82 | HPGD (0.48) | HPGDALDH1A1LMNAMAPK1HTT | |
| SCHEMBL3359451 | 0.80 | HPGD (0.53) | HPGDALDH1A1LMNAMAPK1HTT | |
| SCHEMBL4194204 | 0.80 | HPGD (0.58) | HPGDALDH1A1LMNAMAPK1HTT | |
| SCHEMBL38659958 | 0.80 | HPGD (0.58) | HPGDALDH1A1LMNAMAPK1HTT | |
| SCHEMBL29384629 | 0.80 | HPGD (0.58) | HPGDALDH1A1LMNAMAPK1HTT | |
| SCHEMBL93611 | 0.80 | HPGD (0.58) | HPGDALDH1A1LMNAMAPK1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1928979-B1 | FUNCTIONALIZED PHOTOREACTIVE COMPOUNDS | ROLIC AG (CH) | 2009-03-04 | — | — | EP | disclosed |
| EP-1764405-A1 | Functionalized photoreactive compounds | Rolic AG (CH) | 2007-03-21 | — | — | EP | disclosed |