SCHEMBL2018313

SCHEMBL2018313

C=C(C)C(=O)OC(COc1ccc(C(=O)c2ccccc2)c(O)c1)COc1ccc(C(=O)c2ccccc2)c(O)c1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 5/20 0.54
LMNA P02545 4/20 0.54
MAPK1 P28482 3/20 0.54
ALDH1A1 P00352 3/20 0.54
CYP1A2 P05177 2/20 0.54
PGR P06401 2/20 0.54
SLC6A2 P23975 2/20 0.54
CYP2C19 P33261 2/20 0.54
CYP2D6 P10635 1/20 0.54
PDE4A P27815 1/20 0.54
HRH1 P35367 1/20 0.54
HTT P42858 1/20 0.54
SLC6A3 Q01959 1/20 0.54
PDE4D Q08499 1/20 0.54
MEN1 O00255 2/20 0.47
KMT2A Q03164 2/20 0.47
USP2 O75604 1/20 0.47
GAA P10253 1/20 0.47
KEAP1 Q14145 1/20 0.47
NFE2L2 Q16236 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4607568 0.95 HPGD (0.54) HPGDLMNAMAPK1ALDH1A1CYP1A2
SCHEMBL3359451 0.90 HPGD (0.53) HPGDLMNAMAPK1ALDH1A1CYP1A2
SCHEMBL4339860 0.89 HPGD (0.51) HPGDLMNAMAPK1ALDH1A1CYP1A2
SCHEMBL25925342 0.89 HPGD (0.46) HPGDLMNAMAPK1ALDH1A1CYP1A2
SCHEMBL4339862 0.89 HPGD (0.48) HPGDLMNAMAPK1ALDH1A1CYP1A2
SCHEMBL9447781 0.88 HPGD (0.59) HPGDLMNAMAPK1ALDH1A1CYP1A2
SCHEMBL9447785 0.84 HPGD (0.57) HPGDLMNAMAPK1ALDH1A1CYP1A2
SCHEMBL28452372 0.84 HPGD (0.55) HPGDLMNAMAPK1ALDH1A1CYP1A2
SCHEMBL93301 0.84 HPGD (0.55) HPGDLMNAMAPK1ALDH1A1CYP1A2
SCHEMBL29382170 0.84 HPGD (0.55) HPGDLMNAMAPK1ALDH1A1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 64 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11372267-B2 Contact lens product LARGAN MEDICAL CO., LTD. (TW) 2022-06-28 US claimed
US-20200150460-A1 CONTACT LENS PRODUCT LARGAN MEDICAL CO., LTD. (TW) 2020-05-14 US claimed
US-10578889-B2 Contact lens product LARGAN MEDICAL CO., LTD. (TW) 2020-03-03 US claimed
US-20190317339-A1 CONTACT LENS PRODUCT LARGAN MEDICAL CO., LTD. (TW) 2019-10-17 US claimed
CN-110128897-A A kind of crosslinking with radiation cured flame-retardant coating and preparation method thereof 湖南辰砾新材料有限公司 2019-08-16 CN claimed
US-10371966-B2 Contact lens product LARGAN MEDICAL CO., LTD. (TW) 2019-08-06 US claimed
US-20170227790-A1 CONTACT LENS PRODUCT LARGAN MEDICAL CO., LTD. (TW) 2017-08-10 US claimed
WO-2023161325-A1 OPHTHALMIC DEVICES BAUSCH + LOMB IRELAND LIMITED (IE) 2023-08-31 WO disclosed
US-20230266505-A1 OPHTHALMIC DEVICES JPMORGAN CHASE BANK, N.A., AS SUCCESSOR AGENT 2023-08-24 US disclosed
US-20230266505-A1 OPHTHALMIC DEVICES JPMORGAN CHASE BANK, N.A., AS SUCCESSOR AGENT 2023-08-24 US disclosed
WO-2023148171-A1 MULTIFUNCTIONAL CROSSLINKING AGENTS AND OPHTHALMIC DEVICES FORMED THEREFROM BAUSCH + LOMB IRELAND LIMITED (IE) 2023-08-10 WO disclosed
US-20230244000-A1 MULTIFUNCTIONAL CROSSLINKING AGENTS AND OPHTHALMIC DEVICES FORMED THEREFROM JPMORGAN CHASE BANK, N.A., AS SUCCESSOR AGENT 2023-08-03 US disclosed
US-20230244000-A1 MULTIFUNCTIONAL CROSSLINKING AGENTS AND OPHTHALMIC DEVICES FORMED THEREFROM JPMORGAN CHASE BANK, N.A., AS SUCCESSOR AGENT 2023-08-03 US disclosed
EP-0802219-A2 Coated aliphatic polyester film MITSUI TOATSU CHEMICALS, INC. (JP) 1997-10-22 EP disclosed
US-5663288-A Degradable adhesive film and degradable resin composition MITSUI TOATSU CHEMICALS, INC. (JP) 1997-09-02 US disclosed
US-5489474-A LACTIC ACID BASE POLYMER MITSUI TOATSU CHEMICALS, INC. (JP) 1996-02-06 US disclosed
EP-0677561-A1 Degradable resin composition MITSUI TOATSU CHEMICALS, Inc. (JP) 1995-10-18 EP disclosed
EP-0587069-A1 Degradable adhesive film and degradable resin composition MITSUI TOATSU CHEMICALS, Inc. (JP) 1994-03-16 EP disclosed
US-5244476-A BENZOPHENONE ETHER ESTERS, PROCESSES FOR THEIR PREPARATION, AND THEIR USE FOR IMPROVING THE LIGHT STABILITY OF POLYESTER DYEINGS CASSELLA AG (DE) 1993-09-14 US disclosed
US-4824892-A UV light stabilizer based on benzophenone RIEDEL-DE HAEN AKTIENGESELLSCHAFT (DE) 1989-04-25 US disclosed