SCHEMBL4340459

SCHEMBL4340459

C=C(C(=O)O)C(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)F

nearest known ligand 0.34

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.34
KDM4E B2RXH2 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
USP2 O75604 1/20 0.32
MAPT P10636 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5412521 0.98 KDM4E (0.35) TSHRKDM4ETDP1
SCHEMBL21581916 0.94 KDM4E (0.39) TSHRKDM4ETDP1
SCHEMBL11146351 0.88 THRB (0.40)
SCHEMBL688532 0.88 THRB (0.40)
SCHEMBL4930948 0.85
SCHEMBL8394544 0.85
SCHEMBL28550596 0.85
SCHEMBL1579160 0.83 THRB (0.33)
SCHEMBL4949589 0.82
SCHEMBL1170752 0.82

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 87 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1250616-A4 TUNING OF OPTICAL WAVEGUIDE DEVICES CONTAINING AN ORGANIC MATERIAL CORNING INC (US) 2005-09-28 EP claimed
US-6577787-B2 Tuning of optical waveguide devices containing an organic material CORNING INCORPORATED 2003-06-10 US claimed
JP-3405732-B2 2003-05-12 JP claimed
US-20030081876-A1 TUNING OF OPTICAL WAVEGUIDE DEVICES CONTAINING AN ORGANIC MATERIAL CORNING INCORPORATED 2003-05-01 US claimed
EP-1250616-A1 TUNING OF OPTICAL WAVEGUIDE DEVICES CONTAINING AN ORGANIC MATERIAL CORNING INCORPORATED (US) 2002-10-23 EP claimed
EP-0778804-B1 OPTICAL PELLICLE MEMBRANE TO FRAME ADHESION METHOD MICRO LITHOGRAPHY INC (US) 2002-08-28 EP claimed
US-20010016093-A1 Athermalized integrated optical waveguide devices LUMENTUM OPTICS INC. 2001-08-23 US claimed
EP-1118886-A1 Tuning of optical waveguide devices containing an organic material CORNING INCORPORATED (US) 2001-07-25 EP claimed
WO-2001051969-A1 TUNING OF OPTICAL WAVEGUIDE DEVICES CONTAINING AN ORGANIC MATERIAL CORNING INCORPORATED (US) 2001-07-19 WO claimed
WO-2001051967-A1 ATHERMALIZED INTEGRATED OPTICAL WAVEGUIDE DEVICES CORNING INCORPORATED (US) 2001-07-19 WO claimed
EP-1116973-A1 Athermalized integrated optical waveguide devices Corning Incorporated (US) 2001-07-18 EP claimed
EP-0778804-A4 OPTICAL PELLICLE MEMBRANE TO FRAME ADHESION METHOD MICRO LITHOGRAPHY INC (US) 1998-01-07 EP claimed
EP-0778804-A1 OPTICAL PELLICLE MEMBRANE TO FRAME ADHESION METHOD MICRO LITHOGRAPHY, INC. (US) 1997-06-18 EP claimed
WO-1996009183-A9 OPTICAL PELLICLE MEMBRANE TO FRAME ADHESION METHOD 1996-06-13 WO claimed
WO-1996009183-A1 OPTICAL PELLICLE MEMBRANE TO FRAME ADHESION METHOD MICRO LITHOGRAPHY, INC. (US) 1996-03-28 WO claimed
CN-118119480-A Method and apparatus for in-situ monitoring of chemical mechanical planarization CMP process 崇硕科技公司 2024-05-31 CN disclosed
EP-4355528-A2 METHOD AND APPARATUS FOR IN-SITU MONITORING OF CHEMICAL MECHANICAL PLANARIZATION (CMP) PROCESSES Axus Technology, LLC (US) 2024-04-24 EP disclosed
WO-1990004363-A1 DELIVERING LASER ENERGY THE GENERAL HOSPITAL CORPORATION (US) 1990-05-03 WO disclosed
US-4468425-A Boss formation using low surface energy dams NORTHERN ENGRAVING CORPORATION (US) 1984-08-28 US disclosed
US-4409264-A Boss formation using low surface energy dams NORTHERN ENGRAVING CORPORATION (US) 1983-10-11 US disclosed