Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 14/20 | 0.63 |
| ▸ | ADRB1 | P08588 | 12/20 | 0.63 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.57 |
| ▸ | DRD2 | P14416 | 2/20 | 0.57 |
| ▸ | DRD1 | P21728 | 2/20 | 0.57 |
| ▸ | DRD4 | P21917 | 2/20 | 0.57 |
| ▸ | DRD3 | P35462 | 2/20 | 0.57 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.55 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Formic Acid SCHEMBL4340904 | 1.00 | ADRB2 (0.63) | ADRB2ADRB1ADRA1DDRD2DRD1 | |
| SCHEMBL2793005 | 0.98 | ADRB2 (0.66) | ADRB2ADRB1ADRA1DDRD2DRD1 | |
| SCHEMBL2793001 | 0.98 | ADRB2 (0.66) | ADRB2ADRB1ADRA1DDRD2DRD1 | |
| SCHEMBL13170745 | 0.98 | ADRB2 (0.66) | ADRB2ADRB1ADRA1DDRD2DRD1 | |
| SCHEMBL2794542 | 0.89 | ADRB2 (0.69) | ADRB2ADRB1DRD2DRD1DRD4 | |
| SCHEMBL524584 | 0.89 | ADRB2 (0.69) | ADRB2ADRB1DRD2DRD1DRD4 | |
| SCHEMBL2797776 | 0.88 | ADRB2 (0.53) | ADRB2ADRB1ADRA1DDRD2DRD1 | |
| Fumaric Acid SCHEMBL15300185 | 0.86 | ADRB2 (0.63) | ADRB2ADRB1DRD2DRD1DRD4 | |
| Fumaric Acid SCHEMBL15300183 | 0.86 | ADRB2 (0.63) | ADRB2ADRB1DRD2DRD1DRD4 | |
| SCHEMBL13170245 | 0.85 | ADRB2 (0.64) | ADRB2ADRB1ADRA1DDRD2DRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2057122-A1 | DERIVATIVES OF 4-(2-AMINO-1-HYDROXYETHYL)PHENOL AS AGONISTS OF THE 2 ADRENERGIC RECEPTOR | Laboratorios Almirall, S.A. (ES) | 2009-05-13 | — | — | EP | claimed |
| WO-2008046598-A1 | DERIVATIVES OF 4-(2-AMINO-1-HYDROXYETHYL)PHENOL AS AGONISTS OF THE β2 ADRENERGIC RECEPTOR | LABORATORIOS ALMIRALL, S.A. (ES) | 2008-04-24 | — | — | WO | claimed |