⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Carbimide SCHEMBL28444094 | 1.00 | — | — | |
| Cyclohexane SCHEMBL9860777 | 1.00 | — | — | |
| Cycloheptane SCHEMBL8811487 | 0.76 | ALDH1A1 (0.30) | — | |
| Cycloheptane SCHEMBL4048765 | 0.76 | ALDH1A1 (0.30) | — | |
| Cyclopropane SCHEMBL10596924 | 0.76 | — | — | |
| Carbimide SCHEMBL1235 | 0.76 | — | — | |
| Cyclohexane SCHEMBL11564271 | 0.76 | ALDH1A1 (0.30) | — | |
| Cyclopentane SCHEMBL3823201 | 0.76 | — | — | |
| Cyclopentane SCHEMBL661225 | 0.76 | ALDH1A1 (0.30) | — | |
| Cyclopropane SCHEMBL247293 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11788080-B2 | Modified cleavases, uses thereof and related kits | Encodia, Inc. (US) | 2023-10-17 | — | — | US | disclosed |
| US-20230257727-A1 | MODIFIED CLEAVASES, USES THEREOF AND RELATED KITS | Encodia, Inc. (US) | 2023-08-17 | — | — | US | disclosed |
| US-20230021091-A1 | MODIFIED CLEAVASES, USES THEREOF AND RELATED KITS | Encodia, Inc. (US) | 2023-01-19 | — | — | US | disclosed |
| CN-114716434-A | Nicergoline raw material medicine and synthesis process thereof | 海南久常制药有限公司 | 2022-07-08 | — | — | CN | disclosed |
| EP-3947667-A1 | MODIFIED CLEAVASES, USES THEREOF AND RELATED KITS | Encodia, Inc. (US) | 2022-02-09 | — | — | EP | disclosed |
| US-20210214701-A1 | MODIFIED CLEAVASES, USES THEREOF AND RELATED KITS | Encodia, Inc. (US) | 2021-07-15 | — | — | US | disclosed |
| WO-2020198264-A1 | MODIFIED CLEAVASES, USES THEREOF AND RELATED KITS | Encodia, Inc. (US) | 2020-10-01 | — | — | WO | disclosed |
| US-10131655-B2 | Substituted heterocyclic acetamides as kappa opioid receptor (KOR) agonists | DR. REDDY'S LABORATORIES, LTD. (IN) | 2018-11-20 | — | — | US | disclosed |
| EP-2822928-B1 | SUBSTITUTED HETEROCYCLIC ACETAMIDES AS KAPPA OPIOID RECEPTOR (KOR) AGONISTS | Dr Reddys Laboratories Ltd (IN) | 2018-11-14 | — | — | EP | disclosed |
| US-20170001998-A1 | SUBSTITUTED HETEROCYCLIC ACETAMIDES AS KAPPA OPIOID RECEPTOR (KOR) AGONISTS | DR. REDDY'S LABORATORIES, LTD. (IN) | 2017-01-05 | — | — | US | disclosed |
| WO-2012012410-A2 | KAPPA OPIOID RECEPTOR AGONISTS | DR. REDDY'S LABORATORIES LTD. (IN) | 2012-01-26 | — | — | WO | disclosed |
| EP-2163542-A2 | Bi-functional compound positively charged at first pH and negatively charged at second pH, solid support comprising the bi-functional compound, and method of isolating nucleic acid using the same | Samsung Electronics Co., Ltd. (KR) | 2010-03-17 | — | — | EP | disclosed |
| US-20100063267-A1 | BI-FUNCTIONAL COMPOUND POSITIVELY CHARGED AT FIRST PH AND NEGATIVELY CHARGED AT SECOND PH, SOLID SUPPORT COMPRISING THE BI-FUNCTIONAL COMPOUND, AND METHOD OF ISOLATING NUCLEIC ACID USING THE SAME | SAMSUNG ELECTRONICS CO., LTD (KR) | 2010-03-11 | — | — | US | disclosed |
| US-7396898-B2 | Diamine, acid dianhydride, and reactive group containing polyimide composition prepared therefrom and process of preparing them | KANEKA CORPORATION (JP) | 2008-07-08 | — | — | US | disclosed |
| EP-1345946-B1 | MACROHETEROCYLIC COMPOUNDS USEFUL AS KINASE INHIBITORS | ORTHO MCNEIL PHARM INC (US) | 2005-08-10 | — | — | EP | disclosed |
| US-6828327-B2 | For therapy of chronic pain, neuropathic pain, epilepsy, chronic neurodegenerative conditions, dementia, Alzheimer's disease, schizophrenia, manic depression, neurotraumatic, cognitive decline and ischemia-related diseases | ORTHO-MCNEIL PHARMACEUTICAL, INC. | 2004-12-07 | — | — | US | disclosed |
| US-20040158030-A1 | Diamine, acid dianhydride, polymide composition having reactive group obtained therefrom, and processes for producing these | KANEKA CORPORATION (JP) | 2004-08-12 | — | — | US | disclosed |
| EP-1345946-A1 | MACROHETEROCYLIC COMPOUNDS USEFUL AS KINASE INHIBITORS | Ortho-McNeil Pharmaceutical, Inc. (US) | 2003-09-24 | — | — | EP | disclosed |
| WO-2002046197-A1 | MACROHETEROCYLIC COMPOUNDS USEFUL AS KINASE INHIBITORS | ORTHO-MCNEIL PHARMACEUTICAL, INC. (US) | 2002-06-13 | — | — | WO | disclosed |
| CN-1064679-A | QUINONE DERIVATIVES | EISAI CO LTD (JP) | 1992-09-23 | — | — | CN | disclosed |