⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL93338 | 0.83 | ALDH1A1 (0.44) | — | |
| SCHEMBL11758173 | 0.80 | ALDH1A1 (0.41) | — | |
| SCHEMBL28032778 | 0.80 | ALDH1A1 (0.41) | — | |
| Acetic Acid SCHEMBL11147597 | 0.77 | TSHR (0.39) | — | |
| SCHEMBL50169 | 0.73 | — | — | |
| SCHEMBL19294682 | 0.73 | — | — | |
| SCHEMBL27472108 | 0.73 | — | — | |
| SCHEMBL18741365 | 0.73 | — | — | |
| SCHEMBL19017739 | 0.73 | — | — | |
| SCHEMBL13174858 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 116 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260028600-A1 | TRANSAMINASE POLYPEPTIDES | CODEXIS INC (US) | 2026-01-29 | — | — | US | disclosed |
| US-12448611-B2 | Transaminase polypeptides | CODEXIS, INC. (US) | 2025-10-21 | — | — | US | disclosed |
| US-12378537-B2 | Biocatalysts and methods for synthesizing derivatives of tryptamine and tryptamine analogs | CODEXIS, INC. (US) | 2025-08-05 | — | — | US | disclosed |
| EP-4577644-A1 | BIOCATALYSTS AND METHODS THEREOF | Tesaro, Inc. (US) | 2025-07-02 | — | — | EP | disclosed |
| US-12305201-B2 | Engineered biocatalysts and methods for synthesizing chiral amines | CODEXIS, INC. (US) | 2025-05-20 | — | — | US | disclosed |
| US-20250101389-A1 | BIOCATALYSTS AND METHODS FOR THE SYNTHESIS OF SUBSTITUTED LACTAMS | CODEXIS INC (US) | 2025-03-27 | — | — | US | disclosed |
| US-12163162-B2 | Biocatalysts and methods for the synthesis of substituted lactams | CODEXIS, INC. (US) | 2024-12-10 | — | — | US | disclosed |
| US-20240150732-A1 | TRANSAMINASE POLYPEPTIDES | INNOVATUS LIFE SCIENCES LENDING FUND I, LP, AS COLLATERAL AGENT | 2024-05-09 | — | — | US | disclosed |
| US-11939602-B2 | Transaminase polypeptides | INNOVATUS LIFE SCIENCES LENDING FUND I, LP, AS COLLATERAL AGENT | 2024-03-26 | — | — | US | disclosed |
| WO-2024044657-A1 | BIOCATALYSTS AND METHODS THEREOF | TESARO, INC. (US) | 2024-02-29 | — | — | WO | disclosed |
| US-D646886-S1 | Tip of an umbrella | Pro Performance Sports, L.L.C. (US) | 2011-10-18 | — | — | US | disclosed |
| US-20100209981-A1 | TRANSAMINASE POLYPEPTIDES | CODEXIS, INC. (US) | 2010-08-19 | — | — | US | disclosed |
| WO-2010081053-A2 | TRANSAMINASE POLYPEPTIDES | CODEXIS, INC. (US) | 2010-07-15 | — | — | WO | disclosed |
| US-20070257604-A1 | POLYMERIC COMPOUND AND ORGANIC LUMINESCENCE DEVICE | CANON KABUSHIKI KAISHA (JP) | 2007-11-08 | — | — | US | disclosed |
| EP-1075534-B8 | IMPROVEMENTS IN THE ENZYMATIC SYNTHESIS OF CHIRAL AMINES | CELGRO (US) | 2005-07-06 | — | — | EP | disclosed |
| EP-1075534-B1 | IMPROVEMENTS IN THE ENZYMATIC SYNTHESIS OF CHIRAL AMINES | CELGRO (US) | 2005-05-11 | — | — | EP | disclosed |
| EP-1075534-A4 | IMPROVEMENTS IN THE ENZYMATIC SYNTHESIS OF CHIRAL AMINES | CELGRO (US) | 2003-07-09 | — | — | EP | disclosed |
| EP-1075534-A1 | IMPROVEMENTS IN THE ENZYMATIC SYNTHESIS OF CHIRAL AMINES | Celgro (US) | 2001-02-14 | — | — | EP | disclosed |
| US-6133018-A | Enzymatic synthesis of chiral amines using -2-amino propane as amine donor | CELGRO (US) | 2000-10-17 | — | — | US | disclosed |
| WO-1999046398-A1 | IMPROVEMENTS IN THE ENZYMATIC SYNTHESIS OF CHIRAL AMINES | CELGRO (US) | 1999-09-16 | — | — | WO | disclosed |