SCHEMBL434255

SCHEMBL434255

CN(C)C(=S)S.CN(C)C(=S)S.[NaH]

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TAS2R38 P59533 1/20 0.47
CA1 P00915 3/20 0.44
CA2 P00918 3/20 0.44
CA12 O43570 2/20 0.44
CA9 Q16790 2/20 0.44
HTT P42858 3/20 0.42
ABCB11 O95342 1/20 0.42
CYP2E1 P05181 1/20 0.42
PTGS1 P23219 1/20 0.42
GSDMD P57764 1/20 0.42
ALDH1A1 P00352 3/20 0.41
TP53 P04637 2/20 0.41
HPGD P15428 2/20 0.41
ALOX15 P16050 2/20 0.41
ALOX12 P18054 2/20 0.41
MAPK1 P28482 2/20 0.41
HSD17B10 Q99714 2/20 0.41
TDP1 Q9NUW8 2/20 0.41
HIF1A Q16665 1/20 0.41
LMNA P02545 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL974336 1.00
SCHEMBL27810306 1.00
SCHEMBL21219640 0.96 TAS2R38 (0.44) TAS2R38CA1CA2CA12CA9
SCHEMBL27962112 0.96
Water SCHEMBL6889477 0.96
SCHEMBL28330877 0.96
SCHEMBL37535 0.96
Ethylene SCHEMBL3758453 0.93 TAS2R38 (0.41) TAS2R38CA1CA2CA12CA9
Ethylene SCHEMBL10456278 0.93 TAS2R38 (0.41) TAS2R38CA1CA2CA12CA9
SCHEMBL23045116 0.92

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2012012049-A2 ANTIMICROBIAL COMPLEXES LIU HUIWEN (US) 2012-01-26 WO disclosed