SCHEMBL4343375

SCHEMBL4343375

COCCCc1cccc2c1OCCNC2

nearest known ligand 0.41

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
SSTR4 P31391 19/20 0.39
SSTR1 P30872 3/20 0.36
SSTR2 P30874 3/20 0.36
SSTR3 P32745 3/20 0.36
SSTR5 P35346 3/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL3276939 0.99 SSTR4 (0.39) SSTR4SSTR1SSTR2SSTR3SSTR5
Hydrochloric Acid SCHEMBL3280738 0.81 SSTR4 (0.40) SSTR4SSTR1SSTR2SSTR3SSTR5
Hydrochloric Acid SCHEMBL3277413 0.77 SSTR4 (0.44) SSTR4SSTR1SSTR2SSTR3SSTR5
Hydrochloric Acid SCHEMBL3276374 0.75 SLC6A2 (0.43) SSTR4SSTR1SSTR2SSTR3SSTR5
SCHEMBL2983488 0.73 SSTR4 (0.46) SSTR4
SCHEMBL22513280 0.70 SSTR4 (0.46) SSTR4SSTR1SSTR2SSTR3SSTR5
SCHEMBL13738797 0.70 SSTR4 (0.41) SSTR4SSTR1SSTR2SSTR3SSTR5
Hydrochloric Acid SCHEMBL3276243 0.70 SSTR4 (0.36) SSTR4SSTR1SSTR2SSTR3SSTR5
Hydrochloric Acid SCHEMBL3276239 0.70 SSTR4 (0.36) SSTR4SSTR1SSTR2SSTR3SSTR5
SCHEMBL15676567 0.70 OXTR (0.40)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2123644-A1 BENZOXAZEPINE DERIVATIVES AND USE THEREOF Takeda Pharmaceutical Company Limited (JP) 2009-11-25 EP disclosed