Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 6/20 | 1.00 |
| ▸ | CYP2D6 | P10635 | 5/20 | 1.00 |
| ▸ | MEN1 | O00255 | 4/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 4/20 | 1.00 |
| ▸ | HIF1A | Q16665 | 4/20 | 1.00 |
| ▸ | OPRM1 | P35372 | 4/20 | 1.00 |
| ▸ | MAPT | P10636 | 4/20 | 1.00 |
| ▸ | CYP3A4 | P08684 | 4/20 | 1.00 |
| ▸ | CYP1A2 | P05177 | 4/20 | 1.00 |
| ▸ | CYP2C9 | P11712 | 4/20 | 1.00 |
| ▸ | MAPK1 | P28482 | 4/20 | 1.00 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 1.00 |
| ▸ | SLC6A4 | P31645 | 3/20 | 1.00 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 1.00 |
| ▸ | CHRM2 | P08172 | 2/20 | 1.00 |
| ▸ | CHRM4 | P08173 | 2/20 | 1.00 |
| ▸ | HTR1A | P08908 | 2/20 | 1.00 |
| ▸ | CHRM5 | P08912 | 2/20 | 1.00 |
| ▸ | ADRA2A | P08913 | 2/20 | 1.00 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Flunarizine SCHEMBL16225927 | 1.00 | LMNA (1.00) | LMNACYP2D6MEN1KMT2AHIF1A | |
| Flunarizine SCHEMBL43441 | 1.00 | LMNA (1.00) | LMNACYP2D6MEN1KMT2AHIF1A | |
| Flunarizine SCHEMBL16226917 | 0.99 | LMNA (1.00) | LMNACYP2D6MEN1KMT2AHIF1A | |
| Flunarizine SCHEMBL1321708 | 0.99 | LMNA (1.00) | LMNACYP2D6MEN1KMT2AHIF1A | |
| Flunarizine SCHEMBL10993579 | 0.99 | LMNA (0.97) | LMNACYP2D6MEN1KMT2AHIF1A | |
| Flunarizine SCHEMBL120168 | 0.99 | LMNA (1.00) | LMNACYP2D6MEN1KMT2AHIF1A | |
| Flunarizine SCHEMBL120169 | 0.99 | LMNA (1.00) | LMNACYP2D6MEN1KMT2AHIF1A | |
| SCHEMBL2615163 | 0.99 | LMNA (0.97) | LMNACYP2D6MEN1KMT2AHIF1A | |
| SCHEMBL2615158 | 0.99 | LMNA (0.97) | LMNACYP2D6MEN1KMT2AHIF1A | |
| Flunarizine SCHEMBL27766230 | 0.99 | LMNA (0.97) | LMNACYP2D6MEN1KMT2AHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 12573 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4741492-A2 | NECROSIS INHIBITOR | Linkgevity Limited (GB) | 2026-05-13 | — | — | EP | claimed |
| EP-4255391-B1 | LUMINOL FOR USE IN THE TREATMENT OF SEQUELAE OF A SARS-COV-2 INFECTION | METRIOPHARM AG (CH) | 2026-05-06 | — | — | EP | claimed |
| EP-4704971-A1 | GAMMA STIMULATION AND NEUROMODULATOR COMBINATION THERAPY | Cognito Therapeutics, Inc. (US) | 2026-03-11 | — | — | EP | claimed |
| US-12550885-B2 | Red blood cell storage solutions, solution additives, and methods for improving the storage of red blood cells | UNIVERSITY OF CINCINNATI (US) | 2026-02-17 | — | — | US | claimed |
| EP-4691483-A2 | TREATING REFRACTORY MIGRAINE | Teva Pharmaceuticals International GmbH (CH) | 2026-02-11 | — | — | EP | claimed |
| US-20260001942-A1 | TREATMENT OF HEADACHE DISORDERS AND/OR PSYCHIATRIC SYMPTOMS USING ANTI-CGRP ANTIBODIES, AND COMPOSITIONS AND METHODS RELATED THERETO | H LUNDBECK AS (DK) | 2026-01-01 | — | — | US | claimed |
| WO-2025262247-A1 | TREATMENT OF HEADACHE DISORDERS AND/OR PSYCHIATRIC SYMPTOMS USING ANTI-CGRP ANTIBODIES, AND COMPOSITIONS AND METHODS RELATED THERETO | H. LUNDBECK A/S (DK) | 2025-12-26 | — | — | WO | claimed |
| EP-3515937-B1 | TREATING REFRACTORY MIGRAINE | TEVA PHARMACEUTICALS INT GMBH (CH) | 2025-12-17 | — | — | EP | claimed |
| EP-4658278-A1 | SELECTIVE FIASMA TREATMENT | Valo Health, Inc. (US) | 2025-12-10 | — | — | EP | claimed |
| EP-4655068-A1 | MIGRAINE THERAPY | MedImmune Limited (GB) | 2025-12-03 | — | — | EP | claimed |
| EP-0100037-B1 | MEDICAMENT FOR TREATING SLEEP DISORDERS | Merckle GmbH (DE) | 1987-01-21 | — | — | EP | claimed |
| US-4618598-A | Method of regulating hormone function or release | DUKE UNIVERSITY (US) | 1986-10-21 | — | — | US | claimed |
| EP-0197571-A2 | Novel derivatives of gamma-cyclodextrin | JANSSEN PHARMACEUTICA N.V. (BE) | 1986-10-15 | — | — | EP | claimed |
| US-4612194-A | VITAMIN E, VASODILATORS | ROSHDY ISMAIL | 1986-09-16 | — | — | US | claimed |
| US-4584294-A | Fused tricyclic lactams as angiotensin converting enzyme inhibitors and as antihypertensive agents | MERCK & CO., INC. (US) | 1986-04-22 | — | — | US | claimed |
| EP-0166353-A2 | Benzofused lactams useful as antihypertensive agents and as cholecystokinin antagonists | MERCK & CO. INC. (US) | 1986-01-02 | — | — | EP | claimed |
| EP-0163237-A2 | Di- and tri-peptidal renin inhibitors | MERCK & CO. INC. (US) | 1985-12-04 | — | — | EP | claimed |
| WO-1985002767-A1 | PHARMACEUTICAL COMPOSITIONS CONTAINING DRUGS WHICH ARE INSTABLE OR SPARINGLY SOLUBLE IN WATER AND METHODS FOR THEIR PREPARATION | JANSSEN PHARMACEUTICA N.V. (BE) | 1985-07-04 | — | — | WO | claimed |
| US-4505914-A | BARBITURATES PLUS CINNARIZINE OR FLUNARIZINE | MERCKLE GMBH (DE) | 1985-03-19 | — | — | US | claimed |
| EP-0129189-A2 | Renin inhibitors containing a C-terminal amide cycle and compositions and combinations containing the same | MERCK & CO. INC. (US) | 1984-12-27 | — | — | EP | claimed |