Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | TSHR | P16473 | 1/20 | 0.60 |
| ▸ | F7 | P08709 | 2/20 | 0.56 |
| ▸ | F3 | P13726 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | FAAH | O00519 | 3/20 | 0.52 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.52 |
| ▸ | TERT | O14746 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | BLM | P54132 | 2/20 | 0.50 |
| ▸ | FABP4 | P15090 | 2/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.50 |
| ▸ | PPARG | P37231 | 2/20 | 0.50 |
| ▸ | PPARD | Q03181 | 2/20 | 0.50 |
| ▸ | PPARA | Q07869 | 2/20 | 0.50 |
| ▸ | GMNN | O75496 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL461858 | 1.00 | LMNA (0.60) | LMNAHSD17B10ALDH1A1KMT2AMEN1 | |
| SCHEMBL432892 | 1.00 | LMNA (0.60) | LMNAHSD17B10ALDH1A1KMT2AMEN1 | |
| SCHEMBL5318880 | 1.00 | LMNA (0.60) | LMNAHSD17B10ALDH1A1KMT2AMEN1 | |
| SCHEMBL5318885 | 1.00 | LMNA (0.60) | LMNAHSD17B10ALDH1A1KMT2AMEN1 | |
| SCHEMBL811311 | 1.00 | LMNA (0.60) | LMNAHSD17B10ALDH1A1KMT2AMEN1 | |
| SCHEMBL832473 | 1.00 | LMNA (0.60) | LMNAHSD17B10ALDH1A1KMT2AMEN1 | |
| SCHEMBL23294922 | 1.00 | LMNA (0.60) | LMNAHSD17B10ALDH1A1KMT2AMEN1 | |
| SCHEMBL10445421 | 1.00 | LMNA (0.60) | LMNAHSD17B10ALDH1A1KMT2AMEN1 | |
| SCHEMBL1302120 | 1.00 | LMNA (0.60) | LMNAHSD17B10ALDH1A1KMT2AMEN1 | |
| SCHEMBL21626136 | 1.00 | LMNA (0.60) | LMNAHSD17B10ALDH1A1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009133686-A1 | MEDICAMENTS FOR TREATING ALZHEIMER'S DISEASE | 有限会社アンティアンティ (JP) | 2009-11-05 | — | — | WO | disclosed |