Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | GSK3B | P49841 | 4/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | PLAU | P00749 | 1/20 | 0.47 |
| ▸ | GABRP | O00591 | 1/20 | 0.47 |
| ▸ | GABRD | O14764 | 1/20 | 0.47 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.47 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.47 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.47 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.47 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.47 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.47 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.47 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.47 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.47 |
| ▸ | GABRE | P78334 | 1/20 | 0.47 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4344099 | 1.00 | NPSR1 (0.51) | NPSR1GSK3BGAALMNAHTT | |
| SCHEMBL4346706 | 0.88 | SMN1; SMN2 (0.52) | NPSR1GSK3BLMNAHTTPLAU | |
| SCHEMBL4346697 | 0.88 | SMN1; SMN2 (0.52) | NPSR1GSK3BLMNAHTTPLAU | |
| SCHEMBL4353164 | 0.87 | CDC7 (0.51) | GSK3BKMT2ARPS6KB1HDAC1ADORA2A | |
| SCHEMBL4353161 | 0.87 | CDC7 (0.51) | GSK3BKMT2ARPS6KB1HDAC1ADORA2A | |
| SCHEMBL4346216 | 0.87 | GSK3B (0.58) | GSK3BLMNAKMT2APOLBALDH1A1 | |
| SCHEMBL4346212 | 0.87 | GSK3B (0.58) | GSK3BLMNAKMT2APOLBALDH1A1 | |
| SCHEMBL4355610 | 0.85 | PDPK1 (0.50) | GSK3BKMT2APDPK1HDAC1HDAC6 | |
| SCHEMBL4355602 | 0.85 | PDPK1 (0.50) | GSK3BKMT2APDPK1HDAC1HDAC6 | |
| SCHEMBL4350176 | 0.85 | FGFR1 (0.56) | GSK3BGAALMNAHTTGABRP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2070928-A1 | 7-azaindol-3-ylacrylamides active as kinase inhibitors | NERVIANO MEDICAL SCIENCES S.r.l. (IT) | 2009-06-17 | — | — | EP | claimed |
| EP-2070928-A1 | 7-azaindol-3-ylacrylamides active as kinase inhibitors | NERVIANO MEDICAL SCIENCES S.r.l. (IT) | 2009-06-17 | — | — | EP | disclosed |