Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 18/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4344171 | 1.00 | REN (0.51) | RENCYP3A4PDE4B | |
| SCHEMBL4344175 | 1.00 | REN (0.51) | RENCYP3A4PDE4B | |
| SCHEMBL3972366 | 0.89 | REN (0.44) | REN | |
| SCHEMBL3972369 | 0.89 | REN (0.44) | REN | |
| SCHEMBL3972364 | 0.89 | REN (0.44) | REN | |
| SCHEMBL4348406 | 0.86 | REN (0.51) | RENCYP3A4PDE4B | |
| SCHEMBL4348403 | 0.86 | REN (0.51) | RENCYP3A4PDE4B | |
| SCHEMBL8229111 | 0.83 | REN (0.68) | RENCYP3A4 | |
| SCHEMBL3977593 | 0.83 | PDE4B (0.49) | RENPDE4B | |
| SCHEMBL3977592 | 0.83 | PDE4B (0.49) | RENPDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090281161-A1 | Organic Compounds | MAIBAUM JUERGEN KLAUS | 2009-11-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090281161-A1 | Organic Compounds | REN, ACE, OTC | REN 1/4885CYP3A4 173/4885PDE4B 619/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.