Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 6/20 | 0.37 |
| ▸ | KCNA5 | P22460 | 6/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | GSK3A | P49840 | 1/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
| ▸ | F10 | P00742 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL433487 | 0.92 | SCN9A (0.40) | FGFR1SCN9AGSK3AGSK3B | |
| SCHEMBL432744 | 0.83 | KDM4E (0.39) | FGFR1SCN9AKCNA5HRH3DRD3 | |
| SCHEMBL432647 | 0.81 | SCN9A (0.38) | SCN9ADRD3DRD2GSK3AGSK3B | |
| SCHEMBL432151 | 0.80 | KDM4E (0.37) | FGFR1SCN9AKCNA5HRH3DRD3 | |
| SCHEMBL432153 | 0.78 | GSK3B (0.35) | SCN9AGSK3AGSK3B | |
| SCHEMBL432154 | 0.78 | GSK3B (0.35) | SCN9AGSK3AGSK3B | |
| SCHEMBL431256 | 0.78 | MCHR1 (0.34) | SCN9AGSK3AGSK3B | |
| SCHEMBL431257 | 0.78 | MCHR1 (0.34) | SCN9AGSK3AGSK3B | |
| SCHEMBL432745 | 0.71 | SCN9A (0.36) | SCN9AGSK3AGSK3BF10 | |
| SCHEMBL435039 | 0.71 | MCHR1 (0.34) | SCN9AGSK3AGSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012012366-A1 | PESTICIDAL 3-(ARYLOXY)AZACYCLOALKANES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2012-01-26 | — | — | WO | disclosed |