Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.46 |
| ▸ | HTR1A | P08908 | 7/20 | 0.40 |
| ▸ | BRD4 | O60885 | 3/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.31 |
| ▸ | WNT3A | P56704 | 1/20 | 0.31 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12078457 | 0.88 | PARP1 (0.58) | PARP1HTR1ABRD4SLC6A4 | |
| SCHEMBL14959156 | 0.81 | AKT1 (0.39) | PARP1HTR1ANOTUMCTNNB1WNT3A | |
| SCHEMBL15635817 | 0.81 | PARP1 (0.33) | PARP1HTR1ANOTUMCTNNB1WNT3A | |
| SCHEMBL30748852 | 0.81 | PARP1 (0.33) | PARP1HTR1ANOTUMCTNNB1WNT3A | |
| SCHEMBL7489213 | 0.81 | PARP1 (0.47) | PARP1HTR1ASLC6A4NOTUMCTNNB1 | |
| SCHEMBL11926946 | 0.81 | NOTUM (0.35) | PARP1HTR1ANOTUMCTNNB1WNT3A | |
| SCHEMBL10093043 | 0.81 | PARP1 (0.44) | PARP1HTR1ABRD4SLC6A4NOTUM | |
| SCHEMBL6635190 | 0.81 | PARP1 (0.47) | PARP1HTR1ASLC6A4NOTUMALK | |
| SCHEMBL6585012 | 0.78 | PARP1 (0.49) | PARP1HTR1ASLC6A4NOTUMCTNNB1 | |
| SCHEMBL14268235 | 0.77 | PARP1 (0.31) | PARP1NOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3808737-A1 | PROCESSES FOR PREPARING MEDICAMENTS FOR THE TREATMENT OF CARDIOVASCULAR DISEASES AND INTERMEDIATES FOR USE THEREIN | BIAL - Portela & Ca., S.A. (PT) | 2021-04-21 | — | — | EP | disclosed |
| EP-3044215-B1 | PROCESSES FOR PREPARING MEDICAMENTS FOR THE TREATMENT OF CARDIOVASCULAR DISEASES AND INTERMEDIATES FOR USE THEREIN | BIAL PORTELA & CA SA (PT) | 2020-04-29 | — | — | EP | disclosed |
| EP-2032552-B1 | Mesogenic compounds, liquid crystal medium and liquid crystal display | MERCK PATENT GMBH (DE) | 2016-02-24 | — | — | EP | disclosed |
| EP-2032552-A1 | MESOGENIC COMPOUNDS, LIQUID CRYSTAL MEDIUM AND LIQUID CRYSTAL DISPLAY | Merck Patent GmbH (DE) | 2009-03-11 | — | — | EP | disclosed |
| WO-2007147516-A1 | MESOGENIC COMPOUNDS, LIQUID CRYSTAL MEDIUM AND LIQUID CRYSTAL DISPLAY | MERCK PATENT GMBH (DE) | 2007-12-27 | — | — | WO | disclosed |