Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.30 |
| ▸ | WNT3A | P56704 | 1/20 | 0.30 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.30 |
| ▸ | PGR | P06401 | 1/20 | 0.30 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15635817 | 1.00 | PARP1 (0.33) | PARP1MAPTNPSR1RXFP1NOTUM | |
| SCHEMBL30748780 | 0.89 | PARP1 (0.42) | PARP1MAPTNPSR1RXFP1NR3C1 | |
| SCHEMBL30783445 | 0.81 | AHR (0.38) | MAPTNPSR1RXFP1NOTUM | |
| SCHEMBL4344995 | 0.81 | PARP1 (0.46) | PARP1NOTUMHTR1ACTNNB1WNT3A | |
| SCHEMBL13114495 | 0.78 | ALOX15 (0.38) | PARP1MAPTNPSR1RXFP1NOTUM | |
| SCHEMBL31472199 | 0.78 | NOTUM (0.32) | MAPTNPSR1RXFP1NOTUMCTNNB1 | |
| SCHEMBL11119325 | 0.78 | NOTUM (0.47) | MAPTNPSR1RXFP1NOTUM | |
| SCHEMBL11926946 | 0.78 | NOTUM (0.35) | PARP1NOTUMHTR1ACTNNB1WNT3A | |
| SCHEMBL14959156 | 0.78 | AKT1 (0.39) | PARP1NOTUMHTR1ACTNNB1WNT3A | |
| SCHEMBL4920199 | 0.76 | PARP1 (0.33) | PARP1NOTUMHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4565588-A1 | BIOLOGICALLY ACTIVE COMPOUNDS AND METHODS THEREOF | Suzhou Keen Therapeutics Co., Ltd. (CN) | 2025-06-11 | — | — | EP | disclosed |
| WO-2023241620-A1 | BIOLOGICALLY ACTIVE COMPOUNDS AND METHODS THEREOF | SUZHOU KEEN THERAPEUTICS CO., LTD. (CN) | 2023-12-21 | — | — | WO | disclosed |