Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.45 |
| ▸ | HPGD | P15428 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 7/20 | 0.40 |
| ▸ | HTT | P42858 | 5/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | BCL2 | P10415 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4353768 | 0.84 | SMN1; SMN2 (0.49) | SMN1; SMN2HPGDMAPTHTTALDH1A1 | |
| SCHEMBL4345575 | 0.78 | SMN1; SMN2 (0.46) | SMN1; SMN2HPGDMAPTHTTALDH1A1 | |
| SCHEMBL4343403 | 0.77 | SMN1; SMN2 (0.52) | SMN1; SMN2HPGDMAPTHTTALDH1A1 | |
| SCHEMBL8163960 | 0.74 | GRM4 (0.57) | SMN1; SMN2HPGDMAPTHTTALDH1A1 | |
| SCHEMBL4342422 | 0.74 | SMN1; SMN2 (0.49) | SMN1; SMN2HPGDMAPTHTTALDH1A1 | |
| SCHEMBL4348854 | 0.74 | SMN1; SMN2 (0.45) | SMN1; SMN2HPGDHTTALDH1A1GAA | |
| SCHEMBL4359527 | 0.74 | RAB9A (0.51) | SMN1; SMN2HTTALDH1A1MEN1KMT2A | |
| SCHEMBL4342368 | 0.72 | SMN1; SMN2 (0.52) | SMN1; SMN2HPGDMAPTHTTALDH1A1 | |
| SCHEMBL4345583 | 0.72 | GRM4 (0.39) | SMN1; SMN2HTTALDH1A1MEN1KMT2A | |
| SCHEMBL4342275 | 0.72 | SMN1; SMN2 (0.58) | SMN1; SMN2HPGDMAPTHTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2100876-A2 | New compounds for the inhibition of rotamases and use thereof | Jerini AG (DE) | 2009-09-16 | — | — | EP | claimed |