⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12962497 | 0.75 | — | — | |
| SCHEMBL11568598 | 0.74 | — | — | |
| SCHEMBL407879 | 0.74 | — | — | |
| SCHEMBL2632764 | 0.74 | — | — | |
| SCHEMBL12134091 | 0.74 | — | — | |
| SCHEMBL9052457 | 0.73 | — | — | |
| SCHEMBL6883636 | 0.73 | — | — | |
| SCHEMBL536663 | 0.73 | — | — | |
| Bromide SCHEMBL9580831 | 0.73 | — | — | |
| Hydrochloric Acid SCHEMBL6295547 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 55 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230125751-A1 | METHODS AND COMPOUNDS FOR TREATING PARAMYXOVIRIDAE VIRUS INFECTIONS | GILEAD SCIENCES, INC. | 2023-04-27 | — | — | US | disclosed |
| US-20230027727-A1 | METHODS FOR TREATING ARENAVIRIDAE AND CORONAVIRIDAE VIRUS INFECTIONS | GILEAD SCIENCES, INC. | 2023-01-26 | — | — | US | disclosed |
| EP-4088718-A1 | METHODS FOR TREATING CORONAVIRIDAE VIRUS INFECTIONS | Gilead Sciences, Inc. (US) | 2022-11-16 | — | — | EP | disclosed |
| US-11382926-B2 | Methods for treating Arenaviridae and Coronaviridae virus infections | GILEAD SCIENCES, INC. (US) | 2022-07-12 | — | — | US | disclosed |
| US-11344565-B2 | Methods for the preparation of ribosides | GILEAD SCIENCES, INC. (US) | 2022-05-31 | — | — | US | disclosed |
| EP-3785717-B1 | METHODS FOR TREATING CORONAVIRIDAE INFECTIONS | GILEAD SCIENCES INC (US) | 2022-01-05 | — | — | EP | disclosed |
| US-20210393659-A1 | METHODS FOR TREATING ARENAVIRIDAE AND CORONAVIRIDAE VIRUS INFECTIONS | GILEAD SCIENCES, INC. | 2021-12-23 | — | — | US | disclosed |
| EP-3212175-B1 | METHODS FOR THE PREPARATION OF RIBOSIDES | GILEAD SCIENCES INC (US) | 2021-11-24 | — | — | EP | disclosed |
| EP-1301519-B2 | PRODRUGS OF PHOSPHONATE NUCLEOTIDE ANALOGUES AND METHODS FOR SELECTING AND MAKING SAME | GILEAD SCIENCES INC (US) | 2021-11-10 | — | — | EP | disclosed |
| US-11007208-B2 | Methods for treating arenaviridae and coronaviridae virus infections | GILEAD SCIENCES, INC. (US) | 2021-05-18 | — | — | US | disclosed |
| WO-2012012776-A1 | METHODS AND COMPOUNDS FOR TREATING PARAMYXOVIRIDAE VIRUS INFECTIONS | GILEAD SCIENCES, INC. (US) | 2012-01-26 | — | — | WO | disclosed |
| US-7803788-B2 | Prodrugs of phosphonate nucoleotide analogues | GILEAD SCIENCES, INC. (US) | 2010-09-28 | — | — | US | disclosed |
| US-20080227754-A1 | PRODRUGS OF PHOSPHONATE NUCLEOTIDE ANALOGUES | GILEAD SCIENCES, INC. | 2008-09-18 | — | — | US | disclosed |
| US-7390791-B2 | Which contain phosphoramidate linkages; for retroviral or hepadnaviral therapy; for treatment of HIV/aquired immunodeficiency syndrome; antitumor agents; improved bioavailability | GILEAD SCIENCES, INC. (US) | 2008-06-24 | — | — | US | disclosed |
| US-20060024659-A1 | Prodrugs of phosphonate nucleotide analogues and methods for selecting and making same | GILEAD SCIENCES, INC. | 2006-02-02 | — | — | US | disclosed |
| US-20050159392-A1 | Phosphoramidate linkages; retroviral or hepadnaviral therapy; tissue targeted therapy; HIV/aquired immunodeficiency syndrome; antitumor agents; improved bioavailability | BECKER MARK W (US) | 2005-07-21 | — | — | US | disclosed |
| US-20050124585-A1 | Prodrugs of phosphonate nucleotide analogues | BECKER MARK W (US) | 2005-06-09 | — | — | US | disclosed |
| US-20050124584-A1 | Prodrugs of phosphonate nucleotide analogues | BECKER MARK W (US) | 2005-06-09 | — | — | US | disclosed |
| US-20050124583-A1 | Novel mixed ester-amidates of 9-[2-(phosphonomethoxy)ethyl]adenine (PMPA) for retroviral or hepadnaviral target tissue therapy; viricides; antitumor and -carcinogenic agents; HIV; less toxicity to bystander tissues; greater potency of the parental drug; accumulation in lymphatic tissue | BECKER MARK W (US) | 2005-06-09 | — | — | US | disclosed |
| US-20050009043-A1 | Prodrugs of phosphonate nucleotide analogues | GILEAD SCIENCES, INC. | 2005-01-13 | — | — | US | disclosed |