SCHEMBL536663

SCHEMBL536663

C[C@@H](N)C(=O)C(=O)O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9052457 1.00
2-Oxoisovalerate SCHEMBL2747472 0.79 SLC7A5 (0.43)
Alanine SCHEMBL27491774 0.76 SLC7A5 (0.53)
Alanine SCHEMBL2784274 0.74
Alanine SCHEMBL31 0.74
Alanine SCHEMBL1332110 0.74
Alanine SCHEMBL14764702 0.74 SLC7A5 (0.59)
Oxalic Acid SCHEMBL21145318 0.74 SLC7A5 (0.50)
D-Alanine SCHEMBL2027760 0.74 SLC7A5 (0.59)
Alanine SCHEMBL254290 0.74 SLC7A5 (0.59)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2414399-A1 ANTI-FCRH5 ANTIBODIES AND IMMUNOCONJUGATES AND METHODS OF USE F. Hoffmann-La Roche AG (CH) 2012-02-08 EP disclosed
WO-2010120561-A1 ANTI-FCRH5 ANTIBODIES AND IMMUNOCONJUGATES AND METHODS OF USE GENENTECH, INC. (US) 2010-10-21 WO disclosed