Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 5/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | TTBK1 | Q5TCY1 | 1/20 | 0.42 |
| ▸ | TTBK2 | Q6IQ55 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | TNKS | O95271 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | AXL | P30530 | 1/20 | 0.38 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.38 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.38 |
| ▸ | WNT3A | P56704 | 1/20 | 0.38 |
| ▸ | CDK8 | P49336 | 2/20 | 0.38 |
| ▸ | CDK7 | P50613 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27732331 | 0.86 | AXL (0.41) | CNR2ALDH1A1TNKSMAPTHPGD | |
| SCHEMBL4347102 | 0.85 | MEN1 (0.42) | CNR2KMT2AALDH1A1MAPTMEN1 | |
| SCHEMBL1855794 | 0.80 | MGAM (0.46) | KMT2AALDH1A1TNKSMEN1HPGD | |
| SCHEMBL23970943 | 0.75 | CDK8 (0.41) | ALDH1A1TTBK1TTBK2TNKSHPGD | |
| SCHEMBL19463620 | 0.75 | PIM1 (0.43) | ALDH1A1TNKSMAPTHPGDAXL | |
| SCHEMBL23093275 | 0.75 | NPC1 (0.45) | KMT2AALDH1A1NPC1MAPTRAB9A | |
| SCHEMBL30369396 | 0.74 | NPC1 (0.60) | KMT2AHDAC6NPC1MAPTRAB9A | |
| SCHEMBL5258384 | 0.73 | KMT2A (0.44) | KMT2AALDH1A1HDAC6NPC1MAPT | |
| SCHEMBL4342976 | 0.73 | BRD4 (0.35) | KMT2AALDH1A1HDAC6TNKSNPC1 | |
| SCHEMBL4342973 | 0.73 | BRD4 (0.35) | KMT2AALDH1A1HDAC6TNKSNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090274674-A1 | Heterocyclic Oxime Compounds, Process for Their Preparation and Pharmaceutical Compositions Containing Them | LES LABORATOIRES SERVIER (FR) | 2009-11-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090274674-A1 | Heterocyclic Oxime Compounds, Process for Their Preparation and Pharmaceutical Compositions Containing Them | CYP3A4, CYP2C19, CYP3A43 | CNR2 420/4885KMT2A 1942/4885ALDH1A1 782/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.