Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 8/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4341694 | 0.87 | HPGD (0.42) | HPGDTSHRSMN1; SMN2ALDH1A1GAA | |
| SCHEMBL4349432 | 0.83 | HPGD (0.40) | HPGDTSHRSMN1; SMN2ALDH1A1GAA | |
| SCHEMBL4343757 | 0.83 | HPGD (0.42) | HPGDTSHRSMN1; SMN2ALDH1A1GAA | |
| SCHEMBL4353493 | 0.81 | HPGD (0.43) | HPGDTSHRSMN1; SMN2ALDH1A1GAA | |
| SCHEMBL4342175 | 0.80 | HPGD (0.62) | HPGDTSHRSMN1; SMN2ALDH1A1GAA | |
| SCHEMBL4347843 | 0.80 | HPGD (0.61) | HPGDTSHRSMN1; SMN2ALDH1A1GAA | |
| SCHEMBL4345617 | 0.78 | HPGD (0.42) | HPGDTSHRSMN1; SMN2ALDH1A1GAA | |
| SCHEMBL4350374 | 0.70 | HPGD (0.41) | HPGDTSHRSMN1; SMN2ALDH1A1GAA | |
| SCHEMBL4350159 | 0.70 | TSHR (0.34) | HPGDTSHRSMN1; SMN2ALDH1A1GAA | |
| SCHEMBL4346468 | 0.70 | GAA (0.41) | HPGDTSHRSMN1; SMN2ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2088149-A1 | PHARMACOLOGICALLY ACTIVE N,N'-SUBSTITUTED 3,7-DIAZABICYCLO Ý3.3.1¨NONANES, PHARMACEUTICAL COMPOSITIONS BASED THEREON AND A METHOD FOR THE USE THEREOF | Institute of Physiologically active compunds of the Russian Academy of Sciences (IPAC RAN) (RU) | 2009-08-12 | — | — | EP | claimed |
| EP-2088149-A1 | PHARMACOLOGICALLY ACTIVE N,N'-SUBSTITUTED 3,7-DIAZABICYCLO Ý3.3.1¨NONANES, PHARMACEUTICAL COMPOSITIONS BASED THEREON AND A METHOD FOR THE USE THEREOF | Institute of Physiologically active compunds of the Russian Academy of Sciences (IPAC RAN) (RU) | 2009-08-12 | — | — | EP | disclosed |